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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
PHYTOCHEMICAL DRUG DISCOVERY FOR CENTRAL NERVOUS SYSTEM DISORDERS Understand herbal and plant-based treatments for chronic disorders with this groundbreaking work Due in part to the aging of the global population, disorders of the central nervous system have become an increasingly grave public health concern in recent years. Demand for pharmaceutical treatments has been correspondingly high, but there are many barriers to the successful development of effective synthetic drugs. Phytomedicines, or plant-based and herbal medicines, have proven to be an effective alternative, boasting lower toxicity and cost and higher efficacy, and one that demands greater research and broader-based practition...
Personalized health care to manage diseases and optimized treatment is crucial for everyone to maintain health quality. Significant efforts have been made to design and develop novel nano-enabling therapeutic strategies to cure and monitor diseases for personalized health care. As state-of-the-art, various strategies have been reported to develop personalized nanomedicine to combat against target diseases with no side effects. In this book proposal, we are trying to describe fundamentals of personalized nanomedicine, novel nanomaterials for drug delivery, role of nanotechnology for efficient therapeutics approach, nano-pharmacology, targeted CNS drug delivery, stimuli responsive drug release...
This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed. World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.
Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field.This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds.
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease ...
Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Ph...
This volume in the series, Translational Bioinformatics, provides an up-to-date overview of genomic approaches to asthma. By applying unbiased “-omics” combined with disease-focused and hypothesis-driven approaches, it enhances readers’ understanding of the asthma endotype. Furthermore, it elucidates how progress in -omics research, such as “genomic,” “transcriptomic,” “protomic,” and “metabolomic,” is applied in asthma, and reports on the related series of important breakthroughs in asthma development, classification, prevention and drug sensitivity. Also covering systems biology knowledge and methodologies, computational models and biostatistical methods to analyze big data, this book provides a valuable resource for scientists and researchers in the field of asthma and respiratory diseases.
This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense and protection; cell signaling, mutations; oxidative damage involving lipids, proteins and nucleic acids; membrane trafficking, inflammation, mitochondrial dysfunction, alterations in immunological function and toxicology and hypoxia. Studies on Hepatic Disorders, the latest volume in the Oxidative Stress in Basic Research and Clinical Practice series, provides a comprehensive look at liver topics. It is organized into four sect...