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Graves' Orbitopathy
The significant progress in the understanding of the pathogenesis and the treatment of Graves' orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves' Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.
70 Years of Levothyroxine
This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment. This book is intended for healthcare professionals.
Graves' Orbitopathy
In recent years, close interdisciplinary cooperation of numerous international experts, both clinicians and basic scientists, within the European Group of Graves' orbitopathy (EUGOGO) has yielded much valuable progress and new information, which this publication brings together. Subjects covered include the pathology of Graves' orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Str...
A Case-Based Guide to Clinical Endocrinology
Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions. Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, ca...
Oxford Textbook of Endocrinology and Diabetes
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.
Graves' Orbitopathy
3rd, revised and expanded edition. Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a third edition. What has not changed is the successful and attractive question-and-answer format of the book. In the 3rd, revised and expanded edition, new chapters have been added on co-morbidity, local treatment modalities, novel immunosuppressive therapy, detailed protocols, and questions frequently asked by patients. All chapters of the previous edition have been thoroughly updated. Subjects covered then include the pathology of Graves’ Orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures; and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Additionally, ample consideration is given to the new 2016 ETA/EUGOGO guidelines on the management of GO.
Thyroid Eye Disease
This reference details the anatomy and physiology of the thyroid gland, the environmental and genetic factors associated with Graves' disease, and the immunological mechanisms responsible for related systemic disorders and inflammations of the eye and adjacent tissue structures. Written by more than 60 esteemed international authorities, Thyroid Ey
Extraintestinal Manifestations of Coeliac Disease
Coeliac Disease (CD) affects at least 1% of the population. “Classical” CD refers to gastrointestinal presentations with anaemia and gastrointestinal symptoms. CD can, however, present with extraintestinal manifestations, the commonest of which are dermatitis herpetiformis and neurological presentations (e.g., ataxia, neuropathy, encephalopathy). Recognition and research into the pathophysiology of such manifestations is likely to enhance our understanding of this complex autoimmune disorder.
Thyroid Diseases
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.
