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J. M. Polak and S. R. Bloom For some time Experientia has published, as a unique feature, interdis ciplinary multi-author reviews, giving a comprehensive overview of sub jects regarded as 'growing edges' of science. The enthusiasm shown by the readers was contagious and thus it was felt necessary to compile a special volume dealing with the novel aspects of regulatory peptides. This book covers some of the growing areas in regulatory peptide research and, although it is based on the original volume of Experientia, it is expanded and updated. The topic of 'regulatory peptides' is relatively young and has grown at an unprecedented pace, from the embryonic conception of 'gut hor mones' or 'brai...
The fourth Chinese Peptide Symposium, hosted by Peking University, was held at Chengdu, China on July 21 25, 1996 with 164 participants, including 45 scientists from abroad, representing 12 countries. The four day conference was both intense and spiritually rewarding. Our goal for CPS 96 was to provide a forum for the exchange of knowledge, cooperation and friendship between the international and Chinese scientific communities, and we believe this goal was met. The symposium consisted of 10 sessions with 55 oral and 78 poster presentations, including synthetic methods, molecular diversity and peptide libraries, structure and conformation of peptides and proteins, bioactive peptides, peptide ...
This book reviews in a concise and manageable way the progress in all key areas of natural products chemistry since 1984. The most significant advances are highlighted over a wide field of chemistry, structure, synthesis and biosynthesis. This book provides a unique and superb entry into the vast literature on the subject.
The 3rd edition, the first new one in ten years, includes coverage of molecular levels of detail arising from the last decade's explosion of information at this level of organismic organization. There are 5 new Associate Editors and about 2/3 of the chapters have new authors. Chapters prepared by return authors are extensively revised. Several new chapters have been added on the topic of pregnancy, reflecting the vigorous investigation of this topic during the last decade.The information covered includes both human and experimental animals; basic principels are sought, and information at the organismic and molecular levels are presented. *The leading comprehensive work on the physiology of reproduction*Edited and authored by the world's leading scientists in the field*Is a synthesis of the molecular, cellular, and organismic levels of organization*Bibliogrpahics of chapters are extensive and cover all the relevant literature
This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates, conjugates of biomolecules, and small molecules.
Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible...
Inbreeding, the mating of close kin, and outbreeding, the mating of distant relatives or unrelated organisms, have long been important subjects to evolutionary biologists. Inbreeding reduces genetic diversity in a population, increasing the likelihood that genetic defects will become widespread and deprive a population of the diversity it may need to cope with its environment. Most plants and animals have evolved behavioral and morphological mechanisms to avoid inbreeding. However, today many endangered species exist only in small, very isolated populations where inbreeding is unavoidable, so it has become a concern for conservationists. In this volume, twenty-six experts in evolution, behav...
Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The A...
Block polymers represent another milestone in the preparation of polymers of controlled structure. Catalysts and polymerization methods that allowed the preparation of polymers in which the stereo- and geometric isomerism of the monomer units could be con trolled have indeed been among the major developments in polymer science during the last decade. The synthesis of block polymers, in which the sequence length of the comonomer units can be con trolled, portends equally important developments in the science and technology of polymers. The papers collected in this volume cover primarily the pro ceedings of the most recent symposium on block polymers, sponsored by the Division of Polymer Chemi...
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