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Topic Editors Dr. Bagnoli and Dr. Phogat are employed by GlaxoSmithKline plc. The other Topic Editors Declare no conflict of interest in relation to the Research Topic theme
Why sex matters Among human and nonhuman animals, the prevalence and intensity of infection typically is higher in males than females and may reflect differences in exposure as well as susceptibility to pathogens. Elevated immunity among females is a double-edged sword in which it is beneficial against infectious diseases but is detrimental in terms of increased development of autoimmune diseases. The present book critically reviews the evolutionary origin and the functional mechanisms responsible for sexual dimorphism in response to infection. It emphasizes the value of examining responses in both males and females to improve our understanding about host-pathogen interactions in both sexes. The contributors are experts in their specific disciplines which range from microbiology and immunology to genetics, pathology, and evolutionary biology. The book aims at bringing insight to the treatment and management of infectious diseases; it delineates areas where knowledge is lacking and highlights future avenues of research.
Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro...
Topic Editor Jay Evans is the co-founder, President and CEO of Inimmune Corporation. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
ear Colleagues, The approach to diseases is facing novel frontiers: targeting gene and improving person-centered medicine able to easily and specifically detect early stages of pathologies. The present book includes the most futuristic approaches to the identification of cardiac diseases by means of the most recent discoveries in molecular and genetic diagnosis. The articles will give you the opportunity to think of cardiac diseases as adverse conditions which can be more easily detected by means of technologies and the research spirit of us, physicians dedicated to humans’ care. Please enjoy this reading.
Manual práctico para la detección y el tratamiento integral del síndrome metabólico plantea el objetivo de mostrar las evidencias científicas que se han obtenido en los pacientes mexicanos para entender la historia natural de esta afección. El síndrome metabólico es evolutivo y tiene diferentes subtipos fisiopatológicos, por lo que su expresión clínica es diversa y se clasifica en estadios o etapas clínicas, las cuales son evolutivas e incluyen una etapa temprana, que tiene inicio en una persona que es sedentaria, con antecedentes familiares de enfermedad crónica no transmisible y que lleva a cabo una alimentación no saludable, con incremento del aporte calórico que condiciona...
No Olympic event can rival the rich history and grand spectacle of the marathon. Created for the first modern Olympic Games in Athens in 1896 as a commemoration of the legendary run by the Greek messenger Philippides, the race has endured like no other, producing a century of awe-inspiring competition and unforgettable stories. The Olympic Marathon brings the high drama and rich details of the past 24 Olympic marathon races to life in a way no other book ever has. This definitive resource, written by world-renowned Olympic marathon experts David Martin and Roger Gynn, goes beyond statistics to offer readers a vivid chronicle of the athletes and their memorable marathon performances. Fans wil...
If there is a linchpin to understanding modern European history, it lies in the period of religious strife & scientific progress between the 1550s & 1650s. In The Age of Reason Begins, Will & Ariel Durant bring together a fascinating network of stories in their discussion of the bumpy road toward the Enlightenment. This is the age of great monarchs & greater artists: on the one hand, Elizabeth the First of England, Philip II of Spain & Henry IV of France; on the other, Shakespeare, Cervantes, Montaigne & Rembrandt. It also encompasses the heyday of Bacon, Galileo, Giordano Bruno & Descartes--the fathers of modern science & philosophy. But it is equally an age of extreme violence, a moment in which all Europe was embroiled in the horrible Thirty Years' War--in some respects, the real First World War. Whatever the case, this is a chapter in cultural history one can't set aside. "Mr & Mrs Durant are admirably lucid...This is a book that can be commended very warmly."--The New York Times.