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Mass Spectrometry for Biotechnology
If you investigate biological systems and might use mass spectrometry in your research but need to know more about it, this book is for you. It introduces the fundamental concepts of mass spectrometry and how mass spectrometers work. It also presents recent advancements particularly interesting to bio-researchers in an easy-to-understand manner that does not require extensive background in chemistry, math, or physics. Glossary of basic terms Abundant illustrations Examples of applications Practical tips on using mass spectrometric techniques Useful for peptide, protein, oligonucleotide, and carbohydrate analysis Simplified description of mass spectrometry including: Matrix-Assisted Laser Desorption/Ionization (MALDI) Electrospray Ionization (ESI) Fast Atom/Ion Bombardment (FAB)
The Expanding Role of Mass Spectrometry in Biotechnology
Covers the basic concepts in mass spectrometry as well as advanced topics including protein identification/protein structural analysis, carbohydrate and oligonucleotide analysis. Topics also include pharmacokinetics, high throughput screening, and the recent development of mass spectrometry in clinical diagnosis.
The Exposome
The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview. This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions. Addresses an emerging field that connects with other exciting disciplines Written by a single author who is a leader in the field Includes new content that widely expands on the first edition
All Apes Great and Small
Many of the papers in this volume were first presented at the Third International Great Apes of the World Conference, held July 3-6, 1998 in Kuching, Sarawak, Malaysia. The editors of this volume, the first in a two-volume series, are world renowned, having dedicated most of their lives to the study of great apes. The world's premiere primatologists, ethologists, and anthropologists present the most recent research on both captive and free-ranging African great apes. These scientists, through deep personal commitment and sacrifice, have expanded their knowledge of chimpanzees, bonobos, and gorillas. With forests disappearing, many of these studies will never be duplicated. This volume, and all in the Developments in Primatology book series, aim to broaden and deepen the understanding of this valuable cause.
Biophysical Chemistry
The textbook is intended for the undergraduate and postgraduate students of chemistry, biology and medicine. It covers diverse topics of biophysical chemistry ranging from the structure of cells, lipids, and proteins to nonequilibrium thermodynamics, enzyme catalysis, and fast reaction kinetics. The book discusses the fundamental structural concepts in the first part and provides a systematic account of different experimental techniques such as chromatography, electrophoresis, and gel filtration that are extensively employed in biochemical research in the second part. It also includes typical applications using NMR, ESR, and SPR to comprehend the power of spectroscopic tools in biophysical c...
Mass Spectrometry of Proteins and Peptides
Little more than three years down the line and I am already writing the Preface to a second volume to follow Protein and Peptide Analysis by Mass . What has happened in between these times to make this second venture worthwhile? New types of mass spectrometric instrumentation have appeared so that new techniques have become possible and existing techniques have become much more feasible. More particularly, however, the newer ionization te- niques, introduced for the analysis of high molecular weight materials, have now been thoroughly used and studied. As a result, there has been an en- mous improvement in the associated sample handling technology so that these methods are now routinely appl...
Measuring Mass
Measuring Mass: From Positive Rays to Proteins is part of a celebration of fifty years of the Annual Conference on Mass Spectrometry and Allied Topics. As such, it is intended not only for practitioners of mass spectrometry but also for the lay reader interested in knowing more about the field. Many who practice the art and science of mass spectrometry are unaware of how the technique is applied outside their particular area of expertise. This short exposition will provide the practitioner and lay reader alike with an appreciation for the diverse applications of mass spectrometry in present-day scientific endeavors. Measuring Mass is also intended to celebrate the major events in the history...
Molecular Regulation of Arousal States
Arousal states are processes that include waking, deep sleep, and the dreaming phase of sleep (REM). Molecular Regulation of Arousal States explores the cellular and molecular mechanisms by which sleep and wakefulness are regulated and seeks explanations for the generation of arousal states. It presents step-by-step research protocols that allow investigators to apply the techniques described to a wide range of physiological and behavioral research problems, such as sleep neurobiology and state-dependent disruption of cardiopulmonary control. For the first time, a single source integrates cellular and molecular research techniques with studies of arousal, opening the door to exciting new research methodologies.
