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Topics in Stereochemistry
This seminal series, first edited by Ernest Eliel, responsible for some of the major advances in stereochemistry and the winner of the ACS Priestley Medal in 1996, provides coverage of the major developments of the field of stereochemistry. The scope of this series is broadly defined to encompass all fields of chemical and biological sciences that are founded on molecular and supramolecular interactions. Insofar as chemical, physical, and biological properties are determined by molecular shape and structure, the importance of stereochemistry is fundamental to and consequential for all natural sciences. Topics in Stereochemistry serves as a multidisciplinary series that enriches all of chemis...
Biomolecular Structure and Dynamics
Biomolecular Structure and Dynamics describes recent fundamental advances in the experimental and theoretical study of molecular dynamics and stochastic dynamic simulations, X-ray crystallography and NMR of biomolecules, the structure of proteins and its prediction, time resolved Fourier transform IR spectroscopy of biomolecules, the computation of free energy, applications of vibrational CD of nucleic acids, and solid state NMR. Further presentations include recent advances in UV resonance Raman spectroscopy of biomolecules, semiempirical MO methods, empirical force fields, quantitative studies of the structure of proteins in water by Fourier transform IR, and density functional theory. Metal-ligand interactions, DFT treatment of organometallic and biological systems, and simulation vs. X-ray and far IR experiments are also discussed in some detail. The book provides a broad perspective of the current theoretical aspects and recent experimental findings in the field of biomolecular dynamics, revealing future research trends, especially in areas where theoreticians and experimentalists could fruitfully collaborate.
Enzymes
None
Biologically Active Peptides
Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.
Methods of Biochemical Analysis
Biochemical analysis is a rapidly expanding field and is a key component of modern drug discovery and research. Methods of Biochemical Analysis provides a periodic and authoritative review of the latest achievements in biochemical analysis. Founded in 1954 by Professor David Glick, Methods of Biochemical Analysis provides a timely review of the latest developments in the field.
Biopolymers
Biopolymers deals with the methods of physical characterization and the principles underlying them, with emphasis on quantitative aspects of sequence, conformation, and structure in both laboratory-synthesized and native biopolymers. The book reviews structural units of biopolymers and describes characterization of biopolymers, the available techniques, the evaluation of underlying principles, and experimental applications. Some of these methods include Raman spectroscopy, theoretical conformation analysis, electron microscopy, and morphology of laboratory-synthesized polymers. The text explains the factors controlling conformation of polypeptides, the steric maps of dipeptides, potential en...
Molecular Design and Modeling
Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.
The Enzymes
The Enzymes
Enzyme Regulation and Mechanism of Action
Enzyme Regulation and Mechanism of Action contains the proceedings of the Federation of European Biochemical Societies' Special Meeting on Enzymes held in Dubrovnik, Croatia in 1979. The meeting provided a forum for reviewing advances in understanding the regulation and mechanism of action of enzymes. The discussions are organized around three themes: regulation of enzyme activity; the role of enzymes in the synthesis of nucleic acids and proteins; and proteolytic enzymes. Comprised of 33 chapters, this volume begins with an analysis of partial amino acid sequence of rabbit liver fructose 1,6-bisphophatase and sites of cleavage by proteinases. The reader is then introduced to physiological inactivation of enzymes in yeasts; structure and functions of protein kinases; and control points in the citric acid cycle. Subsequent chapters focus on ligand binding properties and subunit interactions in yeast alcohol dehydrogenase; the role of water in the acceleration of an enzymatic reaction; DNA polymerases of human normal and leukemic cells; and the phylogenetic and developmental aspects of gastric proteinases and their zymogens. This book is intended for enzymologists.
