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A-Dick
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Free-Radical-Induced DNA Damage and Its Repair
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the ...
Reports
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University Record
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Current Trends in Transformation Groups
This book provides an overview of some of the most active topics in the theory of transformation groups over the past decades and stresses advances obtained in the last dozen years. The emphasis is on actions of Lie groups on manifolds and CW complexes. Manifolds and actions of Lie groups on them are studied in the linear, semialgebraic, definable, analytic, smooth, and topological categories. Equivalent vector bundles play an important role. The work is divided into fifteen articles and will be of interest to anyone researching or studying transformations groups. The references make it easy to find details and original accounts of the topics surveyed, including tools and theories used in these accounts.
Fatehpur
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The Early Effects of Radiation on DNA
Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The realisation that DNA is the site of genetic infonnation in cells subsequently focussed attention on DNA as an important target in the lethal and mutagenic effects of ionising radiation. Thus radiation effects upon DNA became an important area for fundamental scientific studies by radiation biologists, chemists and physicists. To a first approximation, the concerns of the three disciplines can be divided by time scales: the physical process of energy deposition from photon or charged 16 12 particle and subsequent relaxation (-10- to 10- secs), followed by chemical 12 2 reactions...
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