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The Adrenergic System in Cardiovascular Physiology and Pathophysiology, 2nd Edition
Cardiovascular diseases pose an enormous clinical challenge, remaining the most common cause of death in the world. ß-adrenoceptors play an important role on cardiac, vascular and/or endothelial function at a cellular level with relevant applications in several cardiovascular diseases, such as heart failure and hypertension. G protein– coupled receptors (GPCRs), including ß-adrenergic receptors, constitute the most ubiquitous superfamily of plasma membrane receptors and represent the single most important type of therapeutic drug target. Sympathetic nervous system hyperactivity, which characterizes several cardiovascular diseases, such as heart failure and hypertension, as well as physio...
The Cardiovascular Adrenergic System
An overview of all the available literature on the various aspects of the regulation of the cardiovascular system`s function and physiology by the adrenergic neurohormonal system, i.e. the catecholamines norepinephrine and epinephrine. Although there are several books describing the adrenergic system`s biology, physiology and pharmacology, and also several excellent books on cardiovascular physiology and pathology, this book focuses exclusively on the interface of these two areas: cardiovascular regulation by the adrenergic system and how it affects cardiovascular diseases and their treatments. Each chapter describe the roles of the adrenergic system first in each cardiovascular cell type (c...
Prevention in Mental Health
The book brings together into a single text the interrelated but different research efforts to translate the current evidence on risk and outcome of severe mental disorders into a preventive perspective. The book also introduces a holistic approach to prevention in mental health, by combining biological, psychological and environmental evidence that attempts to blunt the risk and reduce the number of individuals with mental health vulnerabilities who eventually progress to the manifestation of a severe mental disorder. Finally, the book wants also to highlight the possibility to overcome the single disorder-oriented preventive approach in an attempt to intercept a wider at-risk youth populat...
The Beginning of Futility
Since Picketts failed charge at Gettysburg, the frontal infantry assault had been known as obsolete. Nevertheless fifty years later, Allied military leaders in the Great War persisted in using it as a military tactic. Italian military leaders were no exception not even accepting the deadly effect of machine guns or quick-firing artillery. The Battles of the Isonzo on the Austro-Italian Front have now been classified with Verdun as to intensity and casualty lists. Mountain warfare on the Isonzo River Valley resulted in almost two million casualties from avalanches, frostbite, malaria, cholera, as well as prisoner-of-war starvation. Using the attacco frontale the blood of the illiterate fanti was used as coin to purchase terrain pushing the enemy back leading to Vienna's request to Berlin for help, leading to Caporetto.
Fighting the Great War at Sea
Winner of the John Lyman Book Award for Naval and Maritime Science and Technology. “A compelling and convincing historical analysis of World War I.” —Navy News While the overriding image of the First World War is of the bloody stalemate on the western front, the overall shape of the war arose out of its maritime character. It was essentially a struggle about access to worldwide resources, most clearly seen in Germany’s desperate attempts to counter the American industrial threat, which ultimately drew the United States into the war. This radical new book concentrates on the way in which each side tried to use or deny the sea to the other, and in so doing, describes rapid wartime chan...
Movement Disorders and Sleep – Underlying Mechanisms, Clinical Aspects and Treatment
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Molecular Imaging
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Innovative Technologies and Clinical Applications for Invasive and Non-Invasive Neuromodulation: From the Workbench to the Bedside
The possibility of harvesting the power of electric and magnetic impulses in the human body, commonly referred to as “neuromodulation,” is one of the most recent and promising developments of the modern science. Since the late ´60s, multiple invasive and non-invasive technologies have been developed and tested in experimental and clinical settings with the final aim of modulating the function of the central and peripheral nervous system. Clinical applications include, but are not limited to, common neurological disorders such as Parkinson’s disease and other movement disorders. The bulk of evidence supporting the clinical efficacy of various invasive and non-invasive approaches for ne...
Cognitive Predictive Maintenance Tools for Brain Diseases
New tools for early detection of cognitive brain diseases like depression, epilepsy, parkinson’s disease etc.and the design, analysia, application of such tools. Immense technical value, novelty, importance of work which is valuable for researchers. Incorporates recent technology - breakthrougha in treating brain disease patients.
