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Immunologie is de studie van het immuunsysteem. Het immuunsysteem is uitermate dynamisch en ingewikkeld en heeft als belangrijkste doel het lichaam te beschermen tegen infecties door alle mogelijke micro-organismen en parasieten. Veel verschillende celtypen en moleculen werken samen om zo'n infectie te bestrijden. Het immuunsysteem is altijd actief, gelukkig veelal zonder dat we het merken. Immunologie is een modern vakgebied dat volop in beweging is. Veel ziekten en aandoeningen hebben een immunologische component en tal van nieuwe therapieën zijn gestoeld op immunologische werkingsprincipes.In Immunologie wordt het complexe immuunsysteem van de mens helder en overzichtelijk uiteengezet. I...
This is a Ph.D. dissertation. S. pneumoniae is a major causative agent of serious infections. Besides, the emerging resistance of S. pneumoniae to multiple antibiotic drugs is a major concern in the treatment of infections caused by this micro-organism. Therefore it is important to study the molecular mechanisms that meditate the antibody response to caps-PS. The aim of the study is to better understand the regulation and the molecular mechanisms of the immune response to pneumococcal caps-PS. The present study was undertaken to determine the role of the CD40-CD40L interaction in the murine antibody response to pneumococcal caps-PS antigens.
The rapid developments in immunology in recent immunomodulatory drugs can be distinguished years have dramatically expanded our knowledge of from their beneficial therapeutic effects. mammalian host defence mechanisms. The molecu- Currently,it is only possible to obtain an overview lar mechanisms of cellular interactions during of these various aspects of immunopharmacology immune responses have been unravelled,the intra- by reading a range of immunological,pharmacol- cellular responses involved in signal transduction ical,diagnostic and toxicological literature. Good delineated and an ever-increasing number of soluble immunological textbooks are available, while mediators of immune and infl...
An update on intestinal microbiota and probiotics Our microflora is an individual personal feature, providing a distinct tag to individuals. However, our intestinal microbiome is strongly affected by genetic, nutritional, and other external factors, and evolves with age. An effect of different microbial patterns on health appears very likely as there seem to be specific changes of intestinal microflora associated with various diseases. Specific microbial tags may thus be used as biomarkers of disease: to diagnose it, to monitor its evolution, and eventually to predict its response to treatment. This scenario opens the opportunity for targeting intestinal microflora using probiotics, both for prevention and treatment of an increasing number of conditions. Probiotic therapy is applied either as an adjunct to other treatments or as primary therapy, and evidence of efficacy is accumulating in several conditions, affecting either the intestine or nonintestinal organs. This publication provides an update on probiotics directed at physicians, biologists, biotechnologists, and researchers working in the food industry and agriculture, as well as in the environmental and basic sciences.
June 19-21, 2017 Paris, France Key Topics : Human Vaccines - Infectious & Non Infectious Diseases, Vaccine Research & Development, Cancer Vaccines, Childhood Vaccines, HIV Vaccines, Vaccine Adjuvants & Delivery Technologies, Vaccine Safety & Efficacy, Vaccination for pregnant women, Immunization for Older Adults, Human Preventive & Therapeutic Vaccines, Plant-based Vaccines, Tuberculosis Vaccines, DNA Vaccines, HPV Vaccines, Vaccines against Viral & Bacterial Diseases, Vaccines against Vector-borne Diseases, Mucosal Vaccines, Veterinary vaccines, Hepatitis Vaccines, Fish Vaccines, Travel Immunization,
With a wide variety of investigative approaches, T cell immunology is a vital and open field of study. In T Cell Protocols, Second Edition, an international panel of experts contribute fully updated classic protocols as well as newly established novel techniques for the study of T lymphocyte biology. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters in this volume provide brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections which collect expert tips on troubleshooting and avoiding known pitfalls. Up-to-date and easy to use, T Cell Protocols, Second Edition is an ideal guide for young investigators new to the complex field of immunology as well as a valuable, concise resource for experienced scientists searching for clear, efficacious descriptions of novel methods.
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The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications. These properties of the polysaccharides determine their biological activity and their function in various applications. The role played by polysaccharides in preservation and protection of food, as carriers of nutrients and drugs, their ability to interact with molecules both for efficient delivery as well as improving textures of food colloids and their use as therapeutics are some of the functions discussed.
Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second...