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Hematologic Malignancies
The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is cl...
Biomedical Platforms
An examination of postwar medicine based on the notion of the biomedical platform--the theoretical and clinical meeting ground between the normal and the pathological.
Key West
"Ogle captures this island city in all its quirky charm. Her story breezes along in typical Key West fashion--full of gossip and humor, with the jolt of a good cup of Cuban coffee."--Lee Irby, University of South Florida, St. Petersburg Parrotheads, Hemingway aficionados, and sun worshipers view Key West as a tropical paradise, and scores of writers have set tales of mystery and romance on the island. The city's real story--told by Maureen Ogle in this lively and engaging illustrated account--is as fabulous as fiction. In the early 1800s, the city's pioneer founders battled Indians, pirates, and deadly disease and created wealth beyond their imaginations. In the two centuries since, Key West...
The War on Cancer
After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows that, contrary to frequent announcements of breakthroughs, our current cancer control model cannot eradicate most cancers and the reasons why. Significantly, this book also delineates a way forward via a shift from the discredited cell-kill approach of the past to an integrated, evidence-driven cancer control paradigm based on prevention, early diagnosis, and pharmacogenomics. The author's views are based on data published in mainstream scientific journals and other reliable references, 432 of which are cited.
Cancer and the Search for Selective Biochemical Inhibitors
The world of medicine has become splintered into two factions, that of orthodoxy and its counterpart, alternative or complementary medicine. A problem with alternative medicine is, of course, that of anecdote and hearsay. The solution: the disclosure, in an unassailable fashion, of the underlying biochemical principles for alternative cancer therap
Leukemia
Discusses the history and science of leukemia, its causes and current treatments.
Body Counts
Contributors include Luc Berlivet (INSERM, CNRS, EHESS, Paris), Alberto Cambrosio (McGill University), Sir Iain Chalmers (James Lind Library, Oxford), Nicholas Dodier (INSERM, CNRS, EHESS, Paris), Michael Donnelly (Bard College), Volker Hess (Humboldt-University), Peter Keating (University of Quebec at Montreal), Ann La Berge (Virginia Tech University), Ilana Löwy (INSERM, CNRS, EHESS, Paris), Harry M. Marks (Johns Hopkins University), Lion Murard (INSERM, CNRS, Paris), Mark Parascandola (National Cancer Institute, Bethesda, Maryland), Theodore M. Porter (University of California at Los Angeles), Andrea Rusnock (University of Rhode Island), Christiane Sinding (INSERM, CNRS, EHESS, Paris), and Ulrich Tröhler (Institut für Geschichte der Medizin der Albert-Ludwigs-Universität).
Designing Our Descendants
The Human Genome Project, discoveries in molecular biology, and new reproductive technologies have advanced our understanding of how genetic science may be used to treat persons with genetic disorders. Greater knowledge may also make possible genetic interventions to "enhance" normal human characteristics, such as height, hair or eye color, strength, or memory, as well as the transmittal of such modifications to future generations. The prospect of inheritable genetic modifications, or IGMs, whether for therapeutic or enhancement purposes, raises complex scientific, ethical, and regulatory issues. Designing Our Descendants presents twenty essays by physicians, scientists, philosophers, theolo...
