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In this exciting and timely book new approaches to repairing the parkinsonian brain are described by leading experts. Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. This book gives an overview of the current state-of-the-art research for brain repair, what the challenges are and an indication of what research can provide for the next generation of people with Parkinson’s disease. The comprehensive chapters are geared to an audience of neuroscientists, neurologists, neurosurgeons and anyone interested in how findings in the research laboratory can effectively be transferred to the clinic.
First multi-year cumulation covers six years: 1965-70.
Biochemical Basis of Functional Neuroteratology
Endogenous Peptides and Learning and Memory Processes presents the role of pituitary and central nervous system peptidergic systems in the modulation of memory and learning. This book discusses the various experimental findings concerning the role of peptides in attention, memory, conditioning, opiate tolerance, and amnesia. Organized into five parts encompassing 26 chapters, this book starts with an overview of the possible chemical relationship between melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). This text then discusses the complex behavioral activities of ACTH involving processes that serve the adaptive abilities of the organism, such as memory, learning, ...
First multi-year cumulation covers six years: 1965-70.
Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neurosc...
The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins pla...
While neuroscience has provided insights into the structure and function of nervous systems, hard questions remain about the nature of consciousness, mind, and self. Perhaps the most difficult questions involve the meaning of neuroscientific information, and how to pursue and utilize neuroscientific knowledge in ways that are consistent with some construal of social 'good'. Written for researchers and graduate students in neuroscience and bioethics, Scientific and Philosophical Perspectives in Neuroethics explores important developments in neuroscience and neurotechnology, and addresses the philosophical, ethical, and social issues and problems that such advancements generate. It examines three core questions. First, what is the scope and direction of neuroscientific inquiry? Second, how has progress to date affected scientific and philosophical ideas, and finally, what ethical issues and problems does this progress and knowledge incur, both now and in the future?