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Drugs for Relapse Prevention of Alcoholism
Alcoholism is a pathological behavioural syndrome, characterised by comp- sive alcohol use, craving and relapses, even recurring after many years of abstinence. It is suggested that chronic alcohol abuse leads to persistent changes within several neurochemical pathways in the brain and furthermore that an imprinted drug and addiction memory may scarcely be extinguished. Hence, the question arises as to whether there ought to be a reasonable hope that pharmacological drugs will be developed that interfere with an addiction memory, and as a result, finally lead to a cure? In this book, leading preclinical and clinical experts in the field of alcohol relapse prevention strive to furnish an answ...
Psychiatric Drugs in Children and Adolescents
This book offers a comprehensive survey of the current state of knowledge in the field of neuro-psychopharmacology in childhood and adolescence. In the first part, the essentials of neuro-psychopharmacology are presented in order to provide a deeper understanding of the principles and particularities in the pharmacotherapy of children and adolescents. This part includes information on neurotransmitters and signal transduction pathways, molecular brain structures as targets for psychiatric drugs, characteristics of psychopharmacological therapy in children and adolescents, ontogenetic influences on pharmacokinetics and pharmacodynamics, and pharmacotherapy in the outpatient setting. The part ...
Alcoholism
Despite the plethora of books on alcohol abuse and alcoholism, Alcoholism: Genetic Culpability or Social Irresponsibility is unique. It departs from a generic version of alcoholism; it examines the concepts, rationale, and research findings of all the various aspects of alcoholism and places them into two camps, namely the genetic and the social. Then, Marshall's book deals specifically with the issue of 'social irresponsibility' as a central feature in alcohol abuse; social irresponsibility carries implications for the individual as well as governments' policies. This book will be useful for academics and professionals who are concerned about the widespread problem of alcoholism. Health professional, social workers, and legislators will find this book invaluable in uncovering the nature of this phenomenon.
Behavioral Neurobiology of Alcohol Addiction
The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.
Neuro-Psychopharmaka im Kindes- und Jugendalter
Therapieprinzipien und Besonderheiten schnell verstehen - dabei hilft die komprimierte und einheitliche Darstellung mit zahlreichen Tabellen, Abbildungen und klaren Handlungsanleitungen.
The Brain-Behavioral Connection in Substance Use Disorders and Effects Associated with Injectable Opioid Prescription
The conception of substance dependence as a complex brain disorder calls into question folk-psychological views on the voluntary control of behavior and challenges the popular theory of Cartesian dualism. Although brain abnormalities in substance dependence have long been suspected, only in recent years has research begun to more clearly delineate brain alterations, correlating with measurable changes in behavior. However, no characteristic change has been found and the research findings are equivocal. On the other hand, the brain-behavioral connection in substance dependence offers insight into novel therapeutic approaches and helps to remove the pejorative undertone that often surrounds individuals with opioid or other substance dependence.
