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Risk-sharing in the Pharmaceutical Industry
  • Language: en
  • Pages: 306

Risk-sharing in the Pharmaceutical Industry

The productivity in pharmaceutical research and development faces intense pres sure. R&D expenditures of the major US and European companies have topped US$ 33 billion in 2003 compared to around US$ 13 billion just a decade ago. At the same time, the number of new drug approvals has dropped from 53 in 1996 to only 35 in 2003. Moreover, the protraction of clinical trials has significantly reduced the effective time of patent protection. The consequences are devastating. Monopoly profits have started to decline and the average costs per new drug have reached a re cord level of close to US$ 1 billion today. As a result, any failure of a new sub stance in the R&D process can lead to considerable...

Leading Pharmaceutical Innovation
  • Language: en
  • Pages: 184

Leading Pharmaceutical Innovation

Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. This book investigates and highlights a set of proactive strategies. The authors focus on three sources of pharmaceutical innovation: new management methods, new technologies, and new forms of internationalization. Their findings are illustrated in the case of the Swiss pharmaceutical industry, the leading exporter of pharmaceutical products in percentage of GDP, and some of its main pharmaceutical firms such as Novartis and Hoffmann-La Roche.

The Silver Market Phenomenon
  • Language: en
  • Pages: 515

The Silver Market Phenomenon

TheSilverMarketPhenomenon In the developed countries, the dominant factor in the next society will be something to which most people are only beginning to pay attention: the rapid growth in the older po- lation and the rapid shrinking of the younger generation. Peter F. Drucker The current shift in demographics – aging and shrinking populations – in many countries around the world presents a major challenge to companies and societies alike. As a matter of fact, this is true both for a number of industrialized nations as well as for certain emergingeconomies.However,even thoughthis crucial issue has recently started to attract the attention of scholars, business leaders, and politicians, ...

Lead Markets in Age-Based Innovations
  • Language: en
  • Pages: 352

Lead Markets in Age-Based Innovations

  • Type: Book
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  • Published: 2015-02-18
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  • Publisher: Springer

Nils Levsen focuses on the international diffusion of product and service innovations for elderly users. In particular, the existence and location of lead markets is being investigated. Lead markets are characterized by their early adoption of innovations and their influence on design choice in a subsequent international diffusion process. Finally, two boundary conditions to the applicability of lead market theory are being identified and described.

User Innovators in the Silver Market
  • Language: en
  • Pages: 237

User Innovators in the Silver Market

  • Type: Book
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  • Published: 2015-03-03
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  • Publisher: Springer

In this study among camping tourists of all age groups between 19 and 86 years of age, Konstantin Wellner compares key characteristics regarding innovative behavior of different age groups. The focus of the analysis is on the so-called “Silver Market” segment (consumers of at least 55 years) which gains importance to the demographic shift. Generally, older users are still actively innovating, especially if it relates to age-specific improvements (e.g., comfort and compatibility to other equipment). Analysis by a Structural Equation Model showed that the most important determinant of innovative behavior for older users is technical expertise and that being relatively ahead of trends increases their dissatisfaction with existing products. Additional evidence was found that user with high use experience suffer from functional fixedness.

Value Creation in the Pharmaceutical Industry
  • Language: en
  • Pages: 511

Value Creation in the Pharmaceutical Industry

This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation. A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes. A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.

A Risk-Benefit Perspective on Early Customer Integration
  • Language: en
  • Pages: 253

A Risk-Benefit Perspective on Early Customer Integration

Customer integration in the early innovation phase, considered the method of choice in theory and practice, has shown unexpected side effects that may even outweigh its recognized advantages. As a result, management needs to be able to assess in advance whether the involvement of customers will add overall value to an innovation project. This book develops a mathematical formula to support this decision.

Biomaterials Innovation
  • Language: en
  • Pages: 221

Biomaterials Innovation

Rapid advances in the life sciences means that there is now a far more detailed understanding of biological systems on the cellular, molecular and genetic levels. Sited at the intersection between the life sciences, the engineering sciences and the des

Disseminative Capabilities
  • Language: en
  • Pages: 242

Disseminative Capabilities

Oppat analyzes cooperations in Product Development with a special focus on the Automotive Industry. The in-depth case studies conducted concentrate on joint car development projects between Magna Steyr, an Austrian-based company, and German-based BMW, Mercedes Benz, and Audi.

Reforming America's Health Care System: The Flawed Vision of ObamaCare
  • Language: en
  • Pages: 190