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This issue of Clinics in Laboratory Medicine will focus on Clinical Pathology and is edited by Geza S. Bodor. Topics include, but are not limited to, Steroid measurement / Salivary cortisol measurement, Protein testing by LCMSMS, LCMSMS in the Clinical Laboratory, Laboratory Standards for Clinical LCMSMS, The need to teach LCMSMS to clinical laboratory scientists, MALDI-TOF in the clinical laboratory, MALDI TOF MS in the clinical microbiology laboratory, LCMSMS method development consideration in clinical laboratory practice, Cancer diagnosis using mass spectrometry, Adulteration and LCMSMS drug testing, Diagnosis of inherited metabolic disorders using LCMSMS, Harmonization of LCMSMS protein assays, Vitamin D testing by LCMSMS versus by immunoassay, Pain management testing by LCMSMS, and Development of FDA approved clinical mass spectrometer.
This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, Second Edition serves as a valuable resource for laboratory professionals who are already utilizing mass spectrometry or considering bringing this technology to their labs.
This issue of Clinics in Laboratory Medicine, guest edited by Dr. Indira Guleria, will focus on New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation. Topics include, but are not limited to, T Regulatory cells in Stem cells and Solid organ transplantation, Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation, microRNAs and Transplantation, Role of B Regulatory Cells in Transplant Tolerance, Complement Activation, Biomarkers in Stem Cell Transplantation, Biomarkers of Transplant Tolerance at the Fetomaternal Interface, Signaling molecules in Transplantation and Post-Transplantation Cancer, Donor specific HLA antibodies as Biomarkers of Transplant Rejection, Novel Targets of Immunosuppression in Transplantation, Nanotechnology and Immune therapies in Transplantation, Role of Costimulatory Pathways in Transplant Tolerance, and Microbiota and Immune system and Implications.
This issue of Clinics in Laboratory Medicine, edited by Drs. Julio Delgado and Eszter Lazar-Molnar, will focus on HLA and Disease. Topics include, but are not limited to, The potential impact of NGS in HLA and disease association studies, HLA typing by NGS, HLA Antibody Testing: Evolution and Challenges, Diversity of killer cell immunoglobulin-like receptors and disease, Technical Aspects of Crossmatching in Transplantation, HLA Markers in Celiac Disease, HLA Associations in Drug Hypersensitivity Reactions, HLA in BMT, Post-transplant monitoring, HLA epitope matching in transplantation, and Molecular Testing in Post-Transplant Monitoring.
Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. - Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format - Presents unique and challenging cases in clinical laboratories contributed by experts in the field - Consolidated format that make concepts in toxicology easy to learn and teach - Key learning points highlighted with multiple choice questions
Lyrical, surreal, and yet unsettlingly realistic, The Sinistra Zone swims in the totalitarian backwaters of Eastern Europe Entering a weird, remote hamlet, Andrei calls himself “a simple wayfarer,” but he is in fact highly compromised: he has no identity papers. Taken under the wing of the military zone’s commander, Andrei is first assigned to guard the blueberries that supply a nearby bear reserve. He is surrounded by human wrecks, supernatural umbrellas, birds carrying plagues, albino twins. The bears — and an affair with a married woman — occupy Andrei until his protector is replaced by a new female commander, “a slender creature, quiet,diaphanous, like a dragonfly,” and yet an iron-fisted harridan. As things grow ever more alarming, Andrei becomes a “corpse watchman,” standing guard over the dead to check for any signs of life, and then …
Directory intended to give "medical students and graduate physicians a timely source of detailed information about the many options for pathology training in the United States and Canada." Geographical arrangement. Entries give in narrative such information as programs offered, facilities, community environment, stipends, staff, and application. Training staff index.