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The Alzheimer's Disease Challenge, Volume II
Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II: “The Alzheimer's Disease Challenge”. The repeated failure of clinical trials on the amyloid-based medications and the pessimistic calculations of Alzheimer's disease cost burden for the next few decades present a severe challenge to humankind with severe social implications. In recent years, several alternative diagnostic and treatment procedures have been presented to treat and manage Alzheimer’s disease as it has been nearly impossible to suggest a holistic solution. Several revelations in human biology have highlighted the multiparametric character of the disease. Besides the amyloid aggregation and neurofibrillary tangles that result in Aβ toxicity and tau phosphorylation, processes such as Gene Mutations, Proteins Misfolding, Brain Biochemical and Histopathological Changes, Behavioral Changes, Nutrition and Metabolism Alterations, and Autonomic Dysfunctions due to Central Nervous System dysregulations are common signs and probably early diagnostic biomarkers in most of the Alzheimer's classification categories.
The Neurodegeneration Revolution
The Neurodegeneration Revolution: Emerging Therapies and Sustainable Solutions provides insights into the mechanics, characteristics, behavior, application, and manufacturing of advanced materials such as nanowires, 2D materials, biomaterials, smart materials, and more. The first section discusses the mechanics and electronic and magnetic properties of nanomaterials, photonic, and photonic materials and devices, 2D magnetic materials, smart materials and coatings, metamaterials, and microdevices and sensors. The second section of the book covers manufacturing technologies and methods of previously discussed materials, outlining manufacturing techniques for additive manufacturing of metallic ...
Interdisciplinary Approaches to Altering Neurodevelopmental Disorders
Disorder-assistive and neurotechnological devices are experiencing a boom in the global market. Mounting evidence suggests that approaches based on several different domains should move towards the goal of early diagnosis of individuals affected by neurodevelopmental disorders. Using an interdisciplinary and collaborative approach in diagnosis and support can resolve many hurdles such as lack of awareness, transport, and financial burdens by being made available to individuals at the onset of symptoms. Interdisciplinary Approaches to Altering Neurodevelopmental Disorders is a pivotal reference source that explores neurodevelopmental disorders and a diverse array of diagnostic tools and therapies assisted by neurotechnological devices. While covering a wide range of topics including individual-centered design, artificial intelligence, and multifaceted therapies, this book is ideally designed for neuroscientists, medical practitioners, clinical psychologists, special educators, counselors, therapists, researchers, academicians, and students.
Handbook of Research on Critical Examinations of Neurodegenerative Disorders
Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.
Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health
Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.
Quality Control of Cellular Protein in Neurodegenerative Disorders
Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
Ethnopharmacological Investigation of Indian Spices
Though their usage greatly diminished at the dawn of the scientific area, Indian spices were traditional parts of healthcare for thousands of years. However, over the last decade, largely due to the growth in popularity of complementary and alternative medicine, spices have regained attention due to their physiological and functional benefits. By applying modern research methods to traditional remedies, it is possible to discover what made these spices such effective ailment treatments. Ethnopharmacological Investigation of Indian Spices is a collection of innovative research that analyzes the chemical properties and medical benefits of Indian spices in order to design new therapeutic drugs ...
