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Childhood Trauma in Mental Disorders
This volume presents a comprehensive overview of childhood trauma, considering the psychopathological definition and its neurobiological implications as well as its impact on different psychiatric disorders. The focus on childhood trauma rather than that occurring in adulthood is important due to its general “neuro-psyco-socio” and its specific biological implications, since trauma during childhood impacts directly on neurodevelopment. It has been suggested that early life stress increases vulnerability to psychiatric disorders; however, the exact mechanisms of this association are not yet completely understood. Although childhood trauma could be considered too unspecific to be an important risk factor for individual psychiatric disorders since it seems to occur across the board, it impacts differently on different psychiatric disorders, and it can modulate their clinical expression. Therefore, the assessment of early trauma needs to be included in the clinical evaluation of patients with psychiatric disorders. The volume will be an invaluable tool for psychiatrists, helping them to select suitable pharmacological, psychotherapeutic and rehabilitative treatments.
Temporal Structure of Neural Processes Coupling Sensory, Motor and Cognitive Functions of the Brain
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
I disturbi della consapevolezza nelle malattie neuropsichiatriche
Il presente volume si propone di delineare l’insieme delle attuali conoscenze in campo internazionale sulla consapevolezza di malattia in diverse condizioni neuropsichiatriche (emiplegia conseguente a un danno cerebrale, psicosi, demenze e disturbi dell’umore), con particolare riferimento all’anosognosia e all’insight. Il confronto tra diverse concettualizzazioni e la varietà di manifestazioni cliniche dà luogo ad un quadro molto articolato che necessita di un approccio multidimensionale, specie per quanto riguarda il momento diagnostico. A tal fine, gli autori propongono un’integrazione di diversi contributi sul piano patogenetico, basati su evidenze neuroanatomiche e supportati dalle più recenti tecniche di neuroimmagini. Inoltre, viene suggerito l’utilizzo di una batteria diagnostica complessa in grado di analizzare i diversi aspetti del fenomeno, e di distinguerlo dal meccanismo psicologico difensivo della negazione. La ricerca in questo campo è fondamentale anche per favorire la riabilitazione e la compliance con il trattamento, nonché l’arricchimento delle conoscenze sui processi sottesi alla coscienza e alla consapevolezza nell’essere umano.
The Alzheimer's Disease Challenge
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders
This book provides an up-to-date overview of the role of neurosteroids and neuroactive steroids in the regulation of brain processes and neuropsychiatric disorders. It addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain. It also suggests possible therapeutic approaches to the use of natural occurring or sinthetic neurosteroids. The contributors suggest that neuroactive steroids could have a role in clinical practice.
Time Perception and Dysfunction: Clinical and Practical Implications
Processing time requires a complex set of abilities that dictates how one adapts to the environment. Timing is key in how we communicate, organize our space and understand the world. When timing is intact, it often exists below one's conscious awareness, but when one's ability to process time is disrupted, the effects are noticeable and widespread. To better understand the construct of temporal dysfunction, one has to examine the concept of timing from multiple angles. An integrative approach is required to understand the possible biological, cognitive and psychological etiologies of temporal dysfunction. In addition, expertise in language, measurement and psychopathology are necessary to co...
Handbook of Depression in Alzheimer’s Disease
Advances in healthcare have led to an extended life expectancy throughout the developed world, but cognitive impairment in later life, and Alzheimer's disease (AD) in particular, remains one of the intractable problems which can blight quality of life as we age. Depression in Alzheimer's disease is an additional factor which has a significant impact on disability, disease progression, and caregiver burden. This book, volume 4 of the Advances in Alzheimer’s Disease book series which is published in coordination with the Journal of Alzheimer’s Disease, presents papers which reflect the progress in recent years of research into depression in AD. This research has focused on several areas, i...
Mood and Cognition in Old Age
Improving psychological well-being and cognitive health is now listed as the priority on the healthy aging agenda. Depression and cognitive impairment are great challenges for the elderly population. There have been numerous studies on depression and cognitive impairment and dementia. However, the neural correlates of depression and cognitive impairment have not yet been elucidated. With the development of neuroscience and relevant technologies, studies on anatomical and functional neural networks, neurobiological mechanisms of mood and cognition in old age will provide more insight into the potential diagnosis, prevention and intervention in depression and cognitive impairment. For example,...
