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This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4...
This book aims to provide a comprehensive review of the most up-to-date knowledge of the sources and molecular mechanisms of oxidative stress, and its role in disease and cancer. It also focuses on the novel agents and methods that can be employed to prevent oxidative stress and associated diseases.The authors first review the most recent data on the basic mechanisms of oxidative stress. The second section discusses oxidative stress leading to several diseases and cancers, and in the third section, the strategies employed in the prevention and treatment of oxidative stress-related diseases are discussed.
Indholdet af denne bog: Affinitetsmodning, in vivo, in vitro, virtuel hukommelse T-celle, Th 9-celle, karakterisering, differentiering, fysiologiske funktioner, patofysiologiske funktioner, naturlig dræbercelle, NK-celleceptorer, funktion, nye fund, humoral immunitet, mekanisme, Komplementsystem, Antistoffer, Komplement-afhængig cytotoksicitet, Brug af CDC assays, Antistofafhængig cellulær cytotoksicitet, NK celler, Eosinophils, In vitro assays, Medicinske applikationer, Komplementsystem, Funktioner, Oversigt, Aktivering af komplementer med antigen-associeret antistof, regulering, rolle i sygdom, modulering efter infektioner, klassisk komplementvej, komplementskaskade, klinisk betydning,...
이 책의 내용: 친 화성 성숙, 생체 내, 시험관 내, 가상 메모리 T 세포, Th 9 세포, 특성화, 분화, 생리 기능, 병리 생리 기능, 자연 살해 세포, NK 세포 수용체, 기능, 새로운 발견, 체액 면역, 메커니즘, 보체 시스템, 항체, 보체 의존적 세포 독성, CDC 분석법 사용, 항체 의존성 세포 세포 독성, NK 세포, 호산구, 체외 분석법, 의료 응용 프로그램, 보완 시스템, 기능, 개요, 항원 관련 보충제 활성화 항체, 조절, 질병의 역할, 감염에 의한 조절, 고전적 보체 경로, 보체 캐스케이드, 임상 적 의의, 대체 보체 경로, 캐스케이드, 조절, 질병의 ...