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This book provides a comprehensive overview of various chronic diseases - including their clinical characteristics, diagnostic methods, treatment options, and recent research findings - with a special focus on the psychosexual impacts of these conditions on patients and their partners. Each chapter in the book is dedicated to a specific chronic illness, examining its impact on the patient's sexual health and relationships. The book starts with an overview of the disease and its management, including both traditional and contemporary therapies, diagnostic tools, and international research studies. This is followed by a thorough discussion of the psychosexual consequences of the disease, along...
Inflammatory bowel diseases (IBD), are chronic and progressive diseases. Long-term complications are demolition surgery and colon-rectal cancer (CRC). A treat-to-target approach aims to modify the natural course of these diseases. Targets are pre-defined therapeutic goals demonstrated to prevent end-organ disfunction and disability in the long-term period. According to the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) indications, mucosal healing (MH) and clinical remission are the main targets in IBDs. Recently, the concept of remission and evidence on new targets included histological remission and transmural healing as future new targets. It remains controversial whether achieving these targets is associated with significantly better long-term disease outcomes. In this Research Topic, we aim to systematically review current evidence and future perspectives on therapeutic targets in IBD including mucosal and transmural healing.
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