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This first of two volumes provides up-to-date, methods-related information on ribonuclease functions, assays, and applications. Chapter topics include the identification of, characterization of, and assays for secreted ribonucleases; viral ribonucleases, artificial and engineered ribonucleases, and ribozymes.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5’ or 3’ ends, ribonucleases perform essential roles in gene expression and regulation, genome replication and maintenance, host defense, stress response, and viral strategies of infection. Ribonucleases have also served as highly informative models to understand virtually every aspect of biomolecular structure and function. The fifteen chapters in this volume are written by recognized researchers in the field, and provide in-depth analyses of the major ribonuclease families. Particular f...
Temples are the most prestigious buildings in the urban landscape of ancient Italy, emerging within a network of centres of the then-known Mediterranean world. Notwithstanding the fragmentary condition of the buildings’ remains, these monuments – and especially their richly decorated roofs – are crucial sources of information on the constitution of political, social and craft identities, acting as agents in displaying the meaning of images. The subject of this volume is thematic and includes material from the Eastern Mediterranean (including Greece and Turkey). Contributors discuss the network between patron elites and specialized craft communities that were responsible for the sophist...
The modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans’ susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of these diseases. Components with potential medicinal applications include RIPs, RNases, lectins, protease inhibitors and numerous small compounds. These compounds have shown both preventive and therapeutic effects for humans. This book is a compilation of articles written by internationally renowned experts exploring the different uses of medicinal compounds in human therapeutics. Here we provide a comprehensive outlook on both qualitative and quantitative studies focusing on medicinal plants and animals, and establishing a link between laboratory research discovery and clinical applications.
Unmanned systems are one of the fastest-growing and widely developing technologies in the world, offering many possibilities for a variety of research fields. This book comprises the proceedings of the 2021 International Symposium on Unmanned Systems and the Defense Industry (ISUDEF), a multi-disciplinary conference on a broad range of current research and issues in areas such as autonomous technology, unmanned aircraft technologies, avionics, radar systems, air defense, aerospace robotics and mechatronics, and aircraft technology design. ISUDEF allows researchers, scientists, engineers, practitioners, policymakers, and students to exchange information, present new technologies and developments, and discuss future direction, strategies, and priorities in the field of autonomous vehicles and unmanned aircraft technologies. Covers a range of emerging topics; Addresses current issues on autonomous vehicles and unmanned aircraft; Full proceedings of ISUDEF 2021 held at Howard University.