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Coeliac disease may be manifested with gastrointestinal symptoms, or be latent. It may also be present with dermatitis herpetiformis, dental enamel defects or neurological disorders - especially epilepsy. In the case of the latter symptoms, these appear mostly in relation to occipital seizures, frequently intractable. This book examines these and other neurological manifestations.
In addition to the symptoms and signs of their condition, patients with epilepsy also often experience neuropsychiatric disorders which have a significant impact on their quality of life. Many epileptic patients also suffer from psychosis. Neuropsychiatric development disorders in epileptic children are also common, as are psychiatric problems after surgery for epilepsy. Pre-existing psychiatric problems may result in surgical complications. The aim of this book is to list the current understanding of neuropsychiatric issues in epilepsy. Psychiatrists, epilepsy specialists, neurologists, neuropediatricians and surgeons have joined forces to share their experiences and discuss the advances made in this field. Understanding the mechanisms linking epilepsy to psychiatric disorders makes it possible to establish effective treatments and also improve the quality of life of these patients.
Movement disorders in children: an update with video recordings covers a wide range of disease conditions that are characterized by involuntary movements possibly associated with signs of more diffuse dysfunction of the nervous system. These include both genetically determined and acquired conditions, running a clinical course that may be progressive, static, or paroxysmal. Recent years have witnessed growing interest in the movement disorders of children. There has been an increase in our understanding of the pathogenesis of these disorders, and new perspectives for their diagnosis and treatment have emerged. This book aims to provide neurologists, paediatricians, and specialists in develop...
Idiopathic generalised epilepsies are characterised by strong genetic factors and multiple clinical phenotypes; animal models of untreated epilepsies are relevant to some of the clinical syndromes found in humans. This volume is the first to confront human clinical, animal (experimental) as well as basic and applied genetic data. Main section headings: Current approaches; Familial neonatal and infantile convulsions; Absence seizures and absence epilepsy; Juvenile myoclonic epilepsy and related syndromes; Photosensitivity; Pathophysiology of convulsive seizures; Fundamental and therapeutic aspects.
This text examines epileptic syndromes in infancy, childhood and adolescence.
Authoritative and updated, Epilepsy: A Comprehensive Textbook, 3rd Edition, contains 365 chapters that cover the full spectrum of relevant topics in biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Written by world-renowned authorities and expertly edited by epileptologists Drs. Jerome Engel, Jr., Solomon L. Moshé, Aristea S. Galanopoulou, John M. Stern, Alexis Arzimanoglou, Jacqueline A. French, Renzo Guerrini, Andres M. Kanner, and Istvan Mody, this three-volume work includes detailed discussions of seizure types and epilepsy syndromes, relationships between physiology and clinical events, psychiatric and medical comorbidities, conditions that could be mistaken for epilepsy, and an increasing range of pharmacologic, surgical, and alternative therapies.
A reference book on diagnosis, consequences and management of neonatal and infantile seizures There is a very high incidence of seizures during the first two years of life. This may reflect multiple etiologies depending on the circumstances under which seizures occur. They may have a benign cause but for others they may lead to more devastating consequences. This book provides new insights on how it is best to approach seizures and epilepsy in the first two years of life, to systematically create a blueprint upon which diagnostic and treatment decisions can be based. Ongoing efforts are to understand: - How seizures may occur in the developing brain? - What are their consequences? - Which biomarkers are being developed? - What are the effective treatments to promptly stop ongoing seizures and alter the course of epileptic encephalopathies? The data are highly reflecting the state of the art and also individualize for the particular milieu of the patient in taking into account both nature (i.e. genetics), and nurture (i.e. events that may interfere with normal development) and result in seizures and epilepsy.
The boundaries between epilepsy and movement disorders are difficult to define; some syndromes or diseases may combine the two and many manifestations of one are similar to the other. For the first time, a distinguished, international team of specialists comprehensively examines the clinical, neurophysiological, genetic, pharmacological and molecular factors which underlie the relationships and differences between the two disorders. They examine the methods for investigating motor cortex excitability and the electrophysiological and chemical characteristics of epilepsies which resemble movement disorders. They present a scheme for neurophysiological classification of myoclonic epilepsies and myoclonus and give a detailed analysis of the disorders which cause diagnostic problems in children and adults. There is also an innovative, up-to-date review of the genetic syndromes which associate epilepsy and paroxysmal dyskinesias, and a review of the drugs used to treat, or which may precipitate, epilepsy and movement disorders. This is essential reading for clinicians and neuroscientists.
From pediatric to the elderly, from contractible to refractive, epilepsy is an illness that manifests in many forms and across a range of demographics. In this fascinating volume, the author details more than one hundred instances where health care practitioners faced unusual challenges in treating the disease. All aspects of epilepsy are explored
Since 1984, the year of the publication of its first edition, the famous “Blue Guide” has been the international reference for paediatricians and neuropaediatricians with regard to epileptic syndromes in infants, children and adolescents. This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases. The different backgrounds of the contributors - coordinators and authors – ensure that the book’s longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved. This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.