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Signaling Pathways in Liver Diseases
Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.
Ventilatory Support and Oxygen Therapy in Elder, Palliative and End-of-Life Care Patients
This book provides readers with a comprehensive and up-to-date guide to non-invasive mechanical ventilation in palliative medicine, focusing on why and when it may be necessary. Physicians will find a practical guide to this specific context, particularly focused on pulmonary function and physiology in the elderly, and on ventilatory management in surgery and chronic stable conditions. The book provides detailed information on the rationale for invasive and non-invasive ventilation, the different modes of ventilation, indications and contraindications, prognostic factors, and outcomes. It addresses in detail the role of postoperative mechanical ventilation following various forms of surgery,...
Smart VR/AR/MR Systems for Professionals
Smart VR/AR/MR Systems for Professionals is a comprehensive guide that explores the ground-breaking applications of virtual reality (VR), augmented reality (AR), and mixed reality (MR) in various industries. This book aims to equip practicing professionals with the knowledge and insights they need to harness the full potential of these immersive technologies in their respective fields. Through this book, the authors aim to explore the experimental breakthroughs and cutting-edge methodologies that have emerged in the realm of VR/AR/MR. The book delves deeper into the profound impact these technologies have had on the design process, computer-aided design, healthcare product development, manuf...
The Liver
In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/
“Inside-out” vs “Outside-in” Paradigms in Multiple Sclerosis Etiopathogenesis
Topic Editor Paolo Preziosa received speaker honoraria from Biogen Idec, Novartis, Merck Serono and ExceMED. The rest of Topic Editors declare no competing interests with regards to the Research Topic.
Noninvasive Mechanical Ventilation
The 3rd and updated edition of this book represents a new and unique scientific reference for the medical community on how to understand rationale and applications of noninvasive mechanical ventilation (NIMV). Its aim is to establish the indications of NIMV in critically ill patients in weaning from invasive MV. Nowadays, there is a growing evidence-based medicine that recommends use of NIMV in patients after extubation or in difficult weaning patients also affected by comorbidities. This book has been conceived with the vision or providing the best resources for everyone working in ICUs even if belonging to different specialties (intensive care, anesthesiology, pneumology, emergency medicin...
ESPES Manual of Pediatric Minimally Invasive Surgery
This book is devoted to all the aspects of pediatric minimally invasive surgery and is written under the patronage of the European Society of Pediatric Endoscopic Surgery (ESPES) with the participation of leading international experts on Pediatric MIS. Comprising more than 50 chapters, the book begins with an introductory section describing the general and technical aspects of MIS approaches including laparoscopy, thoracoscopy, retroperitoneoscopy and robotic surgery. The main part of the book is divided into five subsections, each of which focuses on a specific system: thorax, abdomen, urology, gynecology and varia. For each subsection, the book examines several pathologies, accurately desc...
Minimally Invasive Techniques in Pediatric Urology
In the last 10 years, the management of paediatric urological pathologies has been radically transformed; over 70% of all cases can now be treated with minimally invasive techniques. This book is unique in its format, because for each pathology it explores all MIS techniques available for its treatment (laparoscopy, retroperitoneoscopy, robotics, prone position, pneumovesicoscopy, endourology, laser, fetoendoscopy, etc.). Each technique is described in a dedicated chapter, which includes a video of the procedure that can be viewed online. Written by internationally renowned paediatric urology experts, the book offers a valuable toolkit for surgeons, paediatricians and urologists.
Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients
This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infec...
