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Naked Genes
The interaction between new forms of biological life and new forms of social life in modern democracies. The molecular life sciences are making visible what was once invisible. Yet the more we learn about our own biology, the less we are able to fit this knowledge into an integrated whole. Life is divided into new sub-units and reassembled into new forms: from genes to clones, from embryonic stages to the building-blocks of synthetic biology. Extracted from their scientific and social contexts, these new entities become not only visible but indeed “naked”: ready to assume an essential status of their own and take on multiple values and meanings as they pass from labs to courts, from pate...
Bioeconomies
This book explores the promissory discourses and practices associated with the bioeconomy, focusing especially on the transformation of institutions; the creation, appropriation, and distribution of value; the struggle over resources, power, and meaning; and the role of altruism, kinship, and care practices. Governments and science enthusiasts worldwide are embracing the bioeconomy, championing it as the key to health, wealth, and sustainability, while citing it as justification to transform research and regulatory institutions, health and agricultural practices, ethics of privacy and ownership, and conceptions of self and kin. Drawing together studies from Asia, Australia, the Americas, and Europe, this volume encompasses subjects as diverse as regenerative medicine, population health research, agricultural finance, biobanking, assisted reproduction, immigration, breastfeeding, self-help groups, GM fish, and mining sewage.
Stem Cell Epigenetics
Growing evidence suggests that epigenetic mechanisms play a central role in stem cell biology and are vital for determining gene expression during cellular differentiation and governing mammalian development. In Stem Cell Epigenetics, leading international researchers examine how chromatin regulation and bona fide epigenetic mechanisms underlie stem cell renewal and differentiation. Authors also explore how the diversity of cell types, including the extent revealed by single cell omic approaches, is achieved, and how such processes may be reversed or managed via epigenetic reprogramming.Topics discussed include chromatin in pluripotency, stem cells and DNA methylation, histone modifications ...
Reframing Rights
Investigations into the interplay of biological and legal conceptions of life, from government policies on cloning to DNA profiling by law enforcement. Legal texts have been with us since the dawn of human history. Beginning in 1953, life too became textual. The discovery of the structure of DNA made it possible to represent the basic matter of life with permutations and combinations of four letters of the alphabet, A, T, C, and G. Since then, the biological and legal conceptions of life have been in constant, mutually constitutive interplay—the former focusing on life's definition, the latter on life's entitlements. Reframing Rights argues that this period of transformative change in law ...
Bacterial Artificial Chromosomes
For both volumes: Expert investigators describe not only the classic methods, but also the many novel techniques they have perfected for the transfer of large DNAs into the cells of both microbes and animals via large-insert recombinant DNAs. Volume 1 presents readily reproducible techniques for library construction, physical mapping, and sequencing.. An accompanying volume, Volume 2: Functional Studies, provides a wide variety of methods and applications for functional analysis of the DNA-transformed organisms. Besides protocols, each chapter includes scientific reviews, software tools, database resources, genome sequencing strategies, and illustrative case studies.
Organisms and Personal Identity
Over his philosophical career, David Wiggins has produced a body of work that, though varied and wide-ranging, stands as a coherent and carefully integrated whole. In this book Ferner examines Wiggins’ conceptualist-realism, his sortal theory ‘D’ and his human being theory in order to assess how far these elements of his systematic metaphysics connect. In addition to rectifying misinterpretations and analysing the relations between Wiggins’ works, Ferner reveals the importance of the philosophy of biology to Wiggins’ approach. This book elucidates the biological anti-reductionism present in Wiggins’ work and highlights how this stance stands as a productive alternative to emergen...
Lynching Reconsidered
The history of lynching and mob violence has become a subject of considerable scholarly and public interest in recent years. Popular works by James Allen, Philip Dray, and Leon Litwack have stimulated new interest in the subject. A generation of new scholars, sparked by these works and earlier monographs, are in the process of both enriching and challenging the traditional narrative of lynching in the United States. This volume contains essays by ten scholars at the forefront of the movement to broaden and deepen our understanding of mob violence in the United States. These essays range from the Reconstruction to World War Two, analyze lynching in multiple regions of the United States, and e...
Quantified
What is at stake socially, culturally, politically, and economically when we routinely use technology to gather information about our bodies and environments? Today anyone can purchase technology that can track, quantify, and measure the body and its environment. Wearable or portable sensors detect heart rates, glucose levels, steps taken, water quality, genomes, and microbiomes, and turn them into electronic data. Is this phenomenon empowering, or a new form of social control? Who volunteers to enumerate bodily experiences, and who is forced to do so? Who interprets the resulting data? How does all this affect the relationship between medical practice and self care, between scientific and l...
Mechanism and Causality in Biology and Economics
This volume addresses fundamental issues in the philosophy of science in the context of two most intriguing fields: biology and economics. Written by authorities and experts in the philosophy of biology and economics, Mechanism and Causality in Biology and Economics provides a structured study of the concepts of mechanism and causality in these disciplines and draws careful juxtapositions between philosophical apparatus and scientific practice. By exploring the issues that are most salient to the contemporary philosophies of biology and economics and by presenting comparative analyses, the book serves as a platform not only for gaining mutual understanding between scientists and philosophers...
The Benefit of Broad Horizons
More than perhaps anybody else in the world, the Swedish social scientist Björn Wittrock has contributed - both on the intellectual and institutional level - to making a truly global science possible. This book is devoted to an appreciation of his contributions.
