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Mitochondrial Transplantation and Transfer
Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, a volume in the Translational and Applied Bioenergetics series, offers a detailed overview of mitochondrial transplantation across fundamental biology, disease and early therapeutics research. Here, more than twenty experts in the field discuss transplantation and transfer of healthy mitochondria and define future steps to improve new therapeutic applications across a variety of diseases. Emphasis is placed on the physiology of mitochondrial transfer, isolation processes and their applications, transfer methods, and diagnostic and treatment use across cardiovascular, metabolic, and neurological diseases,...
Proximity Labeling
This book provides detailed protocols and untold tips and tricks regarding the most well-known examples of proximity labeling methods, in which the protein of interest is genetically fused to or labeled with an enzyme that can generate short-lived reactive species to non-specifically label molecules within a certain radius of up to twenty nanometers. Beginning with peroxidase-based proximity labeling methods, the volume continues with BioID, proximity labeling methods that describe the proximity ligation assay to detect RNA-DNA interactions, UV cross-linking to demonstrate RNA-protein interactions, and how chemical and enzymatic reactivities can be improved upon DNA-DNA and protein-protein i...
Fundamental Principles of Occupational Health and Safety
Fundamental principles of occupational health and safety, 2nd edition, is a practical guide to developing effective occupational safety and health (OSH) policies and programmes based on the provisions defined in the "core" ILO standards and instruments concerning OSH. It focuses on the key topics essential to promoting and managing national and enterprise OSH systems and presents a concise overview of the issues involved, together with specific guidelines for policy design, implementation and management at both national and enterprise levels. The operational aspects of meeting health and safety requirements are also covered, with detailed sections on legislation and enforcement, occupational...
Contemporary Approaches in Education and Communication
This book presents a collection of papers written by educators and researchers. The topics include the analysis of social science textbooks, the teacher image in newspapers, the relationship between self-efficacy and cognitive level and the role of organizational silence on the loneliness of academics in work life.
Her Naked Skin
Love is just fear I suppose. Masquerading as a fever. Then you explore each other and suddenly you have licence to become totally pedestrian. And ultimately abusive. Militancy in the Suffragette Movement is at its height. Thousands of women of all classes serve time in Holloway Prison in their fight to gain the vote. Amongst them is Lady Celia Cain who feels trapped by both the policies of the day and the shackles of a frustrating marriage. Inside, she meets a young seamstress, Eve Douglas, and her life spirals into an erotic but dangerous chaos. London 1913. A crucial moment when, with emancipation almost in sight, women refuse to let the establishment stand in their way. Rebecca Lenkiewicz's Her Naked Skin premiered at the National Theatre, London, in July 2008.
Wired for Culture: Origins of the Human Social Mind
A fascinating, far-reaching study of how our species' innate capacity for culture altered the course of our social and evolutionary history. A unique trait of the human species is that our personalities, lifestyles, and worldviews are shaped by an accident of birth—namely, the culture into which we are born. It is our cultures and not our genes that determine which foods we eat, which languages we speak, which people we love and marry, and which people we kill in war. But how did our species develop a mind that is hardwired for culture—and why? Evolutionary biologist Mark Pagel tracks this intriguing question through the last 80,000 years of human evolution, revealing how an innate propensity to contribute and conform to the culture of our birth not only enabled human survival and progress in the past but also continues to influence our behavior today. Shedding light on our species’ defining attributes—from art, morality, and altruism to self-interest, deception, and prejudice—Wired for Culture offers surprising new insights into what it means to be human.
Functional Disorders of the Gut
This book provides the busy clinician with a complete and easily accessible guide to the management of this difficult group of patients. The emphasis is on the practical, clinically useful information-- basic science is included for completeness, but is separated from the clinical content for ease of use.
Relativity and Quantum Physics for Beginners
As humanity has expanded its horizon to see things vastly smaller, faster, larger and farther than before, it has been forced to confront preconceptions born of the human experience and create wholly new ways of looking at the world. Relativity and Quantum Physics For Beginners describes the revolutionary theories of relativity and quantum physics and shows how these ideas have led to amazing advances in the understanding of the universe.
