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Clinical Ophthalmic Genetics and Genomics
Clinical Ophthalmic Genetics and Genomics provides an accessible, clinically-focused reference for the evolving field of Genetic Ophthalmology. This well-organised, easy-to-read textbook integrates key concepts with clinical practice and is designed to enhance effective learning and retention of complex material. It includes contributions from recognised leaders in the field and provides expert guidance on the complete spectrum of genetic ophthalmic disorders. - A structured introductory section offering a practical guide to the processes involved in diagnosing patients with genetic ophthalmic disorders - Expert guidance on the complete spectrum of genetic ophthalmic disorders from leading international clinicians and researchers - Well-organised with streamlined, templated chapters and a user-friendly layout that provides quick access to clinically relevant information, and is designed to help ophthalmologists, geneticists, and genetic counsellors in the clinic room
Inherited Chorioretinal Dystrophies
This lavishly illustrated atlas provides indispensable information to clinicians, geneticists and visual scientists working with inherited retinal diseases. It is filled with high-quality images, up-to-date genetic information and comprehensive electrophysiology. The data for each individual disorder have been summarised in an accessible, reader-friendly format for easy reference. The illustrations include colour fundus photographs, fluorescein angiograms, OCT scans, electrophysiological studies and pedigrees. The editors and authors are well-known experts in the field and have drawn upon their extensive experience to produce this unique atlas.
Pediatric Ophthalmology and Strabismus,Expert Consult - Online and Print,4
Pediatric Ophthalmology and Strabismus is your one-stop source for comprehensive coverage of all the pediatric ophthalmic conditions you are likely to encounter in practice. Extensively updated with expert contributions from leaders in the field and now featuring online instructional videos, this ophthalmology reference delivers all the state-of-the-art guidance you need to effectively diagnose and manage even the most challenging eye diseases and disorders seen in children. Take a holistic approach to patient management that considers the family and ensures optimal doctor-patient relationships.Get a balanced view of etiology, diagnosis, and management, and access unique guidance on the prac...
Genetics in Ophthalmology
The objective of this publication is to enhance mutual understanding and communication between ophthalmologists, molecular geneticists, genetic counselors and biomedical researchers. In the introductory chapter, current genetic paradigms and experimental genetic approaches relevant to the nature of hereditary disorders are discussed. The following contribution on the epidemiology of hereditary ocular disorders provides an excellent reference to geneticists as well as clinicians. Myopia is presented as an example of a complex clinical phenotype where genes and environment interact. Further molecular ophthalmogenetic topics, such as corneal dystrophies, cataract, glaucoma, opticus neuropathy, non-syndromic and syndromic pigmentary retinopathies, defects of vitamin A metabolism and macular dystrophies including age-related macular degeneration, are investigated in depth. The volume concludes with a survey of color vision deficiencies, a discussion of animal models and gene therapy, and a useful description of technical devices supporting patients who are losing sight.
Genomics and Clinical Medicine
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
Genomic Medicine
The first edition of Genomics and Clinical Medicine provided an overview of genomics-based advances in disease susceptibility, diagnosis, and prediction of treatment outcomes in various areas of medicine. Since its publication, the science of genomics has made tremendous progress, and exciting new developments in biotechnology and bioinformatics have created possibilities that were inconceivable only a few years ago. This completely revised second edition of Genomic Medicine reflects the rapidly changing face of applied and translational genomics in the medical and health context and provides a comprehensive coverage of principles of genetics and genomics relevant to the practice of medicine.
Normal
The nameless narrator first appears to fit the stereotype of a meticulous killer untroubled by normal emotions. He researched 18-year-old Sarah Abbott, who was taking a year off from school before heading to Oxford, killed her in her house, and carefully cleaned up afterward. On returning to his van, however, he discovers that he has locked its keys inside. A brick through the van's window solves that problem, but later, back at the victim's house, he runs into a friend of Sarah's, Erica Shaw, who winds up in a cage in the basement of the narrator's garage. His bumbling continues throughout. In a big departure from the standard serial killer trope, he begins nonpredatory relationships with three different women. He even falls in love with one of them. Those who have no trouble accepting a humanized serial killer will be most satisfied.
The Black Eagle
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Essential Karate Book
The Essential Karate Book is an informative, illustrated guide to the techniques, philosophy and practice of karate. With 20 chapters covering practically every aspect of karate, this in-depth reference will assist students and instructors as they plot their course through karate instruction, benefiting those at all levels. The Essential Karate Book contains 200 diagrams mapping out moves with 300 step-by-step photographs and companion videos, making it a comprehensive general karate reference for Western audiences. Readers of this karate guide will learn about: Stances, blocks, strikes and kicks Preparing your body through warm-ups, stretching, and conditioning through karate-specific exercises Kata grading and fighting (kumite) techniques and competition rules Martial arts weapons (kobudo), and MMA (Mixed Martial Arts) applications The origins and history of karate Required behavior, clothing and etiquette, as well as the fundamentals of karate and the different styles that share them The Essential Karate Book is a must-have for any martial arts enthusiast, from beginners to black belts!
