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Allen Davis looks at the influence of settlement-house workers on the reform movement of the progressive era in Chicago, New York, and Boston. These workers were idealists in the way they approached the future, but they were also realists who knew how to organize and use the American political system to initiate change. They lobbied for a wide range of legislation and conducted statistical surveys that documented the need for reform. After World War I, settlement workers were replaced gradually by social workers who viewed their job as a profession, not a calling, and who did not always share the crusading zeal of their forerunners. Nevertheless, the settlement workers who were active from the 1880s to the 1920s left an important legacy: they steered public opinion and official attitudes toward the recognition that poverty was more likely caused by the social environment than by individual weakness,
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Flak-Catchers explores the ways in which riot commissions-the institutional bodies appointed by an executive in the aftermath of a race riot to determine a riot timeline, investigate causes, and offer prescriptions for change-have dealt with racial violence in the United States over the last century. In studying five American riots and their commissions this book shows that riot commissions only serve to give the appearance of strong and responsive government action during uncertain times. They primarily benefit the instituting body by focusing on a restoration of law and order while undermining any larger civil rights message.
Molecular Diagnostics covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by exmples from the authors' own epertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. - Examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders - Includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders - Identification of genetically modified organisms (GMO's) - Forensic analysis and every-day issues in a diagnostic laboratory - Discusses ethics, genetic counselling and quality management
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As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.
This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence. Molecular Diagnosis of Genetic Diseases, Second Edition offers diagnostic molecular geneticists a unique opportunity to sharpen their scientific skills in the design of assays, their execution, and their interpretation.