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This book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated. The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, a...
This volume contains the proceedings of the twenty-second International Conference on Medical Informatics Europe MIE 2009, that was held in Sarajevo, Bosnia and Herzegovina, from 30 August to 2 September 2009. The scientific topics present in this proceedings range from national and trans-national eHealth roadmaps, health information and electronic health record systems, systems interoperability and communication standards, medical terminology and ontology approaches, and social networks to Web, Web 2.0, nd Semantic Web solutions for patients, health personnel, and researchers. Furthermore, they include quality assurance and usability of medical informatics systems, specific disease management and telemedicine systems, including a section on devices and snsors, drug safety, clinical decision support and medical expert systems, clinical practice guidelines and protocols, as well as issues on privacy and security. Moreover, bioinformatics, biomedical modeling and simulation, medical imaging and visualizatio and, last but not least, learning and education through medical informatics systems are parts of the included topics.
This volume offers a comprehensive and up-to-date overview of the major surgical procedures performed on elderly patients. With advancing age the conditions that require surgery normally increase in incidence, and today all surgeons around the globe can be considered “geriatric surgeons”. The latest anesthesiological procedures, the technical improvements and an increased medical knowledge of the comorbities impact have brought extraordinary advances in this field, but this should not allow us to forget that a careful assessment of elderly patients is necessary before undertaking surgery, since also the simplest surgical procedures could alter the delicate psychophysical equilibrium of these “frail” patients. Introduced by a demographic panorama and analysis, the book describes the anesthesiological management, the preoperative assessment and preparation, the perioperative care, and hemostasis control connected with the main surgical pathologies: gastrointestinal, endocrine, neoplastic, vascular and hepato-biliary, as well with traumatic and non-traumatic emergencies. It will be an invaluable, easy-to-use resource for clinicians, researchers and trainees alike.
ear Colleagues, The approach to diseases is facing novel frontiers: targeting gene and improving person-centered medicine able to easily and specifically detect early stages of pathologies. The present book includes the most futuristic approaches to the identification of cardiac diseases by means of the most recent discoveries in molecular and genetic diagnosis. The articles will give you the opportunity to think of cardiac diseases as adverse conditions which can be more easily detected by means of technologies and the research spirit of us, physicians dedicated to humans’ care. Please enjoy this reading.
Chronic degenerative diseases are one of the major public health problems, particularly those affecting the nervous system. They are characterized by the degeneration of specific cell populations that include several pathologies which contribute significantly to morbidity and mortality in the elderly population. Therefore, in recent years, the study of neuroscience has gained significant importance. Most of these neurodegenerative disorders are the result of a complex interaction between genetic and environmental factors that generate progression and can even determine its severity. The presence of mutations in genes as LRRK2, SNCA, PARK7, PARK2 or PINK1 is associated with Parkinson's diseas...
This book focuses specifically on the management of cardiovascular disease in elderly patients with particular frailties and in the “oldest old”. It is clearly explained how treatment in these patients differs from that in patients in their seventies who respond well to therapies and do not present frailties or organ failures. Although not young, the latter patients can be treated almost like any other patient, according to established guidelines. In contrast, the frail, compromised elderly and the oldest old require specific measures that target their needs, including with respect to underlying renal conditions. The book considers all those pathologies that have a high prevalence in the general population, explaining advanced treatment concepts and all aspects of assessment. Key clinical points are highlighted, and the text is supplemented with numerous informative figures and tables. The authors are respected experts, for the most part geriatric physicians, and the book is especially addressed to cardiologists, who may lack the described targeted information and treatment tools.