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Practical Transfusion Medicine Practical Transfusion Medicine, Sixth Edition The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017. The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of information than standard handbooks on transfusion medicine, whilst being more concise and approachable than a stand...
This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts sheet format. Database accession numbers and useful adjuncts such as Request forms, worksheets for PCR/enzyme digests also serve to benefit the user. The information is clearly presented and easily accessib...
Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.
Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin
Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most frequent and devastating adverse drug reactions encountered by physicians. This thoroughly updated fifth edition from international experts Professors Warkentin and Greinacher is the gold standard for accurate diagnosis and management of this cond
Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most potentially devastating and frequent adverse drug reactions encountered by physicians. This Fourth Edition reinforces its standing as the leading guide to the accurate diagnosis and management of HIT by identifying key signs and symptoms of this d
Transfusion medicine is rapidly changing from what was a relatively narrowly focused field with a limited diagnostic and therapeutic scope to one that embraces fundamental elements of immunology, stem cell biology, the inflammatory response and hemostatis. This shift in focus is in response to the accelerated pace of advances in biomedical research. No longer constrained to diagnoses based on blood group serology or to therapies based on a limited number of blood components and derivatives, transfusion medicine is redefining itself through the clinical application of modern biotechniques. In Emerging Technologies in Transfusion Medicine examples of the emerging technologies that are transforming both diagnostic and therapeutic aspects of the field are highlighted, offering a deeper understanding and an informed evaluation necessary for their application.
The mechanisms underlying human immunoglobulin variable gene expression are poorly understood. For instance, certain immunoglobulin variable gene segments are preferentially used both during early development and in various autoimmune disorders and B-cell neoplasms. This volume addresses topics - such as human immunoglobulin gene organisation, rearrangement, transcription and somatic mutation, and B-cell and immunoglobulin gene repertoire development - selected for their relevance to the interpretation of the multitude of human immunoglobulin gene studies in the normal B-cell repertoire and in various B-cell disorders.
3ème tome de la série Âme de Lycan. Raphaël a grimpé dans la hiérarchie lycane. En même temps, il développe de nouvelles capacités, inquiétant Mégane. Personne ne peut expliquer ce qui lui arrive, hormis une légende datant de plusieurs siècles. Alors, quand le loup disparait, la communauté est inquiète. Surtout que les vampires continuent leurs exactions sanglantes, aidés par deux louves au tempérament de feu. L’insécurité grandissante met tous les loups en danger. Mais l’espoir renaît dans le cœur des lycans. Une énergie nouvelle se propage dans la communauté et qui pourra tous les sauver : la révélation d’un Epsilon.