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This is the first comprehensive collection of court decisions dealing exclusively with the relationship between European Community law and the national laws of the Member States. It contains 90 decisions given between 1962 and 1993 by both the Community's Court of Justice (20 cases) and the courts of the 12 Member States (70 cases). The volume includes the recent decisions of national courts concerning the Maastricht Treaty. Key recurring topics of the decisions are the supremacy and direct effect of Community law, its impact on national sovereignty and constitutional rights, and the remedies available before national courts for its enforcement. All the texts are presented in English, having been translated wherever necessary. Each decision is preceded by a concise summary and key-word heading. The volume also includes a systematic introduction, digest of key-word headings, table of cases, and detailed index.
The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Simi...
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Parenting and educating a child with an autism spectrum disorder (ASD) is a unique experience for many reasons. Too often, the K-12 school system overlooks the needs of children with ASDs or educators find themselves unprepared to provide a learning environment that fulfills these needs. Parents of children with ASDs must also stay informed on autism support services, school system practices, developmental pediatrics, and more in order to be an active voice in how their children are supported within the school system. Understanding Parent Experiences and Supporting Autistic Children in the K-12 School System shares the experiences of children with ASDs in order to develop more supportive practices for these children as they navigate the K-12 system. It also offers best practices, strategies, and information for educators to provide a sufficient learning environment to support children with ASDs within their classrooms. Covering topics such as assistive tools, inclusive practices, and parent experiences, it is an ideal resource for K-12 administration and faculty, educators, pre-service teachers, policymakers, parents, researchers, and academicians.