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Viral Replication Cycle - From Pathogenesis and Immune Response to Diagnosis and Therapy
Viruses pose a huge burden on public health systems and the economy worldwide. In the case of humans, viruses make up about two-thirds of all new human pathogens. Both DNA and RNA viruses can cause acute, persistent, or latent infections, as they can integrate their genome into the host DNA, such as the endogenous retroviruses, which can be associated with a wide variety of cancers in animals and humans. In recent years, viruses have emerged not only as a health threat but also as a potential alternative for producing new diagnostic tools as well as prophylactic/therapeutic approaches to defeat viral diseases. This book provides a broadly comprehensive series of reviews describing the replication strategies used for both DNA and RNA viruses, their interaction with the host immune system, and their potential role in tumorigenicity and cancer immunotherapy as applied to various viruses of critical relevance for human or animal diseases.
Dengue Fever in a One Health Perspective
Dengue Fever in a One Health Perspective underlines important aspects of dengue virus, the most prevalent and life-threatening arbovirus in the world. Over three sections, chapters cover such topics as biological and environmental aspects, physiopathology, molecular biology, diagnosis, and control strategies. The first section provides knowledge on basic aspects of dengue virus biology and its emergence and re-emergence associated to environmental changes. The second section includes two chapters on dengue immunopathology, a drawback in disease control and vaccine development. Finally, the third section examines molecular biology tools employed in dengue virus immunopathogenesis studies, diagnosis, drug design, and in the use of vectors as sentinels in surveillance and vector biology studies.
Enfermedad y muerte en Ciudad Juárez en 1918
La investigación de prevalencia de enfermedades en las ciudades de la frontera norte de México con Estados Unidos representa un desierto que poco ha sido explorado. No se conoce con exactitud de qué enfermaba y moría la gente en las primeras décadas del siglo XX. La trascendencia de esta breve investigación tiene relación con la enfermedad y la mortalidad en la década de los veinte en Ciudad Juárez, radica en el fortalecimiento de la historiografía de las ciudades fronterizas de la región norte de México, además, contribuye a diseñar una etiología de la enfermedad desde el punto de vista histórico, pues poco se conoce de padecimientos y causas de muerte de miles de personas que habitaron la ciudad durante una época que es considerada de escándalo y de vicio para dar paso a lo que hasta hoy día se conoce como leyenda negra.
Un otoño que perduró en la memoria
Aunque esta historia coincide con algún periodo de la Revolución mexicana, la obra no pretende ser parte de esa historiografía. Los autores aspiran a relatar una historia de hombres, mujeres y niños, indefensos en su gran mayoría, que sufrieron frío, desnutrición, pobreza, miseria y diversas enfermedades que afectaban principalmente a la población de la capital poblana. La reconstrucción del centro y de las zonas afectadas por los sitios militares de 1863 y 1867, que habían destruido partes importantes de la zona poniente del entramado urbano, no pudo resolver la pobreza y crisis social en la que se encontraba sumida la mayoría de la población.Durante la década de 1910, las di...
Revista biomédica
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A History of Spain
The present work is an attempt to give in one volume the main features of Spanish history from the standpoint of America. It should serve almost equally well for residents of both the English-speaking and the Spanish American countries, since the underlying idea has been that Americans generally are concerned with the growth of that Spanish civilization which was transmitted to the new world. One of the chief factors in American life today is that of the relations between Anglo-Saxon and Hispanic America. They are becoming increasingly important. The southern republics themselves are forging ahead; on the other hand many of them are still dangerously weak, leaving possible openings for the n...
