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Nutrition, Diet and Cancer
Chemoprevention of cancer has been the focus of intensive research for more than two decades. Epidemiological evidence has shown a small, but significant association between fruit and vegetable intake and a reduction in cancer risk. Diet may account for about thirty five percent of cancer. Large claims have been made for the effectiveness of particular diets in determining one's risk of developing cancer, ranging from protection against cancer initiation, progression and metastasis. A wide array of dietary components has been demonstrated to be as effective in fighting off cancer. Towards an increased understanding of the nutrition, excercise and diet in preventing cancer or inhibiting its p...
Nutritional Oncology
Nutritional oncology is an increasingly active interdisciplinary field where cancer is investigated as both a systemic and local disease originating with the changes in the genome and progressing through a multi-step process which may be influenced at many points in its natural history by nutritional factors that could impact the prevention of cancer, the quality of life of cancer patients, and the risk of cancer recurrence in the rapidly increasing population of cancer survivors.Since the first edition of this book was published in 1999, the idea that there is a single gene pathway or single drug will provide a cure for cancer has given way to the general view that dietary/environmental fac...
Murine Models, Energy Balance, and Cancer
This volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long...
Cancer Research
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Animal Models in Cancer Drug Discovery
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre...
Science News
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Cómo matar de hambre al cáncer
Jane McLelland tenía solo 30 años cuando le diagnosticaron cáncer. Unos años más tarde estaba en fase 4 (o terminal) y se había extendido a sus pulmones. Le dieron una esperanza de vida de doce semanas, pero se negó a creer que no existieran medicamentos o terapias eficaces. Su formación científica le permitió examinar y asimilar cientos de artículos de investigación y la conclusión a la que llegó la dejó asombrada. ¿Habría una nueva forma de tratar el cáncer entre la extrema toxicidad de la quimioterapia de dosis alta y las terapias alter-nativas? ¿Una que pudiera sacar lo mejor de la medicina convencional, así como de la complementaria? ¿Sería posible encontrar un tra...
