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"Contents of this Ph.D. dissertation include: Cerebral complications in the neonatal intensive care, Gastro-intestinal complications in neonatal intensive care, Near-infrared spectroscopy, Measurement of cerebral blood flow and cerebral blood volume by NIRS, Measurement of cerebral oxygenation, Literature review of measurements of cerebral oxygenation and cerebral blood flow using near-infrared spectroscopy in neonates, Continuous measurement of cerebral blood flow and cerebral haemoglobin oxygen saturation with NIRO 300 in Neonatology, Use of NIRO 300 monitor, Measurement of the different parameters, Measurement of normal values of TOI in prematurely born infants, Conclusions."
From the 40th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Bruges, Belgium in August 2012, this volume covers aspects of clinical applications, muscle oxygenation, cancer, measurement technologies, oxygen transport modelling and Near-Infrared Spectroscopy (NIRS), cell metabolism and brain oxygenation. Each topic was presented by one or two invited speakers, and a series of contributed talks.
Preterm birth affects over 15 million newborns worldwide each year and is the main contributor of neonatal mortality and morbidity. While neonatal survival following preterm birth continues to improve, this has not been matched by a decline in neurological outcome. There is still a high prevalence of motor problems, executive dysfunction, and cognitive impairment in infants born preterm. Improved neuroimaging has helped to describe different types of neonatal brain injuries in this population and has given a better understanding of underlying pathogenesis. However, therapies are still lacking and there is a great need to find novel strategies to improve injury and functional outcome.
This book focuses on Least Squares Support Vector Machines (LS-SVMs) which are reformulations to standard SVMs. LS-SVMs are closely related to regularization networks and Gaussian processes but additionally emphasize and exploit primal-dual interpretations from optimization theory. The authors explain the natural links between LS-SVM classifiers and kernel Fisher discriminant analysis. Bayesian inference of LS-SVM models is discussed, together with methods for imposing spareness and employing robust statistics. The framework is further extended towards unsupervised learning by considering PCA analysis and its kernel version as a one-class modelling problem. This leads to new primal-dual support vector machine formulations for kernel PCA and kernel CCA analysis. Furthermore, LS-SVM formulations are given for recurrent networks and control. In general, support vector machines may pose heavy computational challenges for large data sets. For this purpose, a method of fixed size LS-SVM is proposed where the estimation is done in the primal space in relation to a Nystrom sampling with active selection of support vectors. The methods are illustrated with several examples.
The ISOTT 2001 local organizing committee was pleased to welcome over 140 delegates from around the world to the 29th annual general meeting of the International Society for Oxygen Transport to Tissue. The meeting was held in historic Philadelphia, USA, on the campus of the University of Pennsylvania from August 11 to 15, 2001. In the tradition of ISOTT, the conference was a total immersion experience. Attendees were encouraged to eat together and spend their evenings relaxing together in a style that maximized exchange of ideas and interactions of younger scientists with their more senior colleagues. Delegates participated in a total of 122 presentations including poster displays, selected ...
Hemodynamics and Cardiology, a volume in Dr. Polin’s Neonatology: Questions and Controversies Series, offers expert authority on the toughest cardiovascular challenges you face in your practice. This medical reference book will help you provide better evidence-based care and improve patient outcomes with research on the latest advances. Reconsider how you handle difficult practice issues with coverage that addresses these topics head on and offers opinions from the leading experts in the field, supported by evidence whenever possible. Find information quickly and easily with a consistent chapter organization. Get the most authoritative advice available from world-class neonatologists who have the inside track on new trends and developments in neonatal care. Stay current in practice with coverage on issues such as the clinical implications of near-infrared spectroscopy in neonates, MRI imaging and neonatal hemodynamics, and hybrid management techniques for congenital heart disease.
Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. - Stay fully up to date in this fast-changing field with Hemodynamics and Cardiology, 3rd Edition. - A new editorial team and a completely redesigned volume with state-of-the-art chapters on neonatal hemodynamics. - New chapters on the role of delayed cord clamping/cord ...
This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles. Both overview and the most recent, advanced techniques for oxygen measurement are presented. Articles and peer reviewers include those from leaders in their field. Topics such as molecular signaling in the organismal and tumor response to low levels of local oxygenation, hypoxia inducible factor (HIF) , cancer metabolism, individual human and animal response to oxygen changes monitored by optical/near infrared spectroscopy/ tomography to novel electron resonance spectroscopy and spectroscopic imaging, instrumentation, progress in blood substitute research, retinal physiology, cellular hypoxia, mitochondrial function; brain oxygenation and function; oxygen transport in sports, hypoxia in diseases and clinical care. Chapters 10 and 19 of this book are open access under a CC BY 4.0 license.