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The Sounds of Mandarin
Mandarin Chinese is the most widely spoken language in the world today. In China, a country with a vast array of regional and local vernaculars, how was this “common language” forged? How did people learn to speak Mandarin? And what does a focus on speech instead of script reveal about Chinese language and history? This book traces the surprising social history of China’s spoken standard, from its creation as the national language of the early Republic in 1913 to its journey into postwar Taiwan to its reconfiguration as the common language of the People’s Republic after 1949. Janet Y. Chen examines the process of linguistic change from multiple perspectives, emphasizing the experienc...
ADME-Enabling Technologies in Drug Design and Development
A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given a...
Handbook of Materials for Nanomedicine
In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. The materials discussed include liposome-scaffold systems, elastic liposomes, targeted liposomes, solid lipid nanoparticles, lipoproteins, exosomes, porous inorganic nanomaterials, silica nanoparticles, and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.
Foundations of Confucian Thought
This ambitious work focuses on the world of Chinese thought during the Chunqiu (Springs and Autumns) period (722-451 B.C.E.), the two and a half centuries directly preceding and partly overlapping the time of Confucius, China's single most influential thinker. Ideas developed by Chunqiu statesmen and thinkers formed the intellectual milieu of Confucius and his disciples and contributed directly to the intellectual flowering of the Zhanguo (Warring States) era (453-221 B.C.E.), the formative period of the Chinese intellectual tradition. This study is the first attempt to systematically reconstruct major intellectual trends in pre-Confucian China. Foundations of Confucian Thought is based on an exploration of the Zuo zhuan, the largest pre-imperial historical text. Relying on meticulous textual and linguistic analysis, Yuri Pines argues that hundreds of the speeches of Chunqiu statesmen recorded in the Zuo zhuan were not, as has been argued, invented by the compiler of the treatise but reproduced from earlier sources, thus making it an authentic reflection of the Chunqiu intellectual tradition. By tracing changes in ideas and concepts throughout the Chunqiu period, Pines reconstructs
The Animal and the Daemon in Early China
Exploring the cultural perception of animals in early Chinese thought, this careful reading of Warring States and Han dynasty writings analyzes how views of animals were linked to human self perception and investigates the role of the animal world in the conception of ideals of sagehood and socio-political authority. Roel Sterckx shows how perceptions of the animal world influenced early Chinese views of man's place among the living species and in the world at large. He argues that the classic Chinese perception of the world did not insist on clear categorical or ontological boundaries between animals, humans, and other creatures such as ghosts and spirits. Instead the animal realm was positioned as part of an organic whole and the mutual relationships among the living species—both as natural and cultural creatures—were characterized as contingent, continuous, and interdependent.
Fairplay
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The Oxford Handbook of Sociolinguistics
This major new survey of sociolinguistics identifies gaps in our existing knowledge base and provides directions for future research.
The Sociolinguistics of Voice in Globalising China
This book deploys and develops the notion of voice in an investigation of China’s rapidly reshuffling society. The book is structured around two aspects of the voicing process in contemporary China: (1) stratification of voice, which addresses the stabilizing condition of voice; and (2) restratification of voice that draws attention to the dynamics of the system of which the order is reshuffling and not yet apparent. This structure allows us to unveil the hidden forces played out in the voice making process and to stratifying and re-stratifying process of contemporary Chinese society in which some people are making themselves heard whereas others are losing voice. Despite its importance and usefulness, voice has been under theorized in recent decades. The ambitions of this book therefore are to invest serious efforts in developing the notion and to position it in the center of the theoretical toolkits available to students and scholars within and outside sociolinguistics.
