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Cancer Risk Evaluation
An overview of the different approaches to cancer risk assessment of environmental factors - including "-omics" technologies, discussing the strengths and weaknesses of the methods in different fields. The main focus is on the carcinogenic effects of ionizing and non-ionizing radiation, demonstrating the difficulties in accurately assessing those factors that may or may not pose a significant cancer risk. The book extends the view to a broader context of risk assessment, highlighting various aspects of risk management. Written by leading experts in the field, this is a resource for policy makers and professionals in health risk assessment, and public health workers, as well as oncologists and researchers in academia. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
Chromosomal Alterations
The book helps the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
Chromosomal Alterations
Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered. Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.
Chromosomal Aberrations
Chromosomale Mutationen sind eine der m|glichen Ursachen f}r Ver{nderungen der Erbinformation. Neben grunds{tzlichen As- pekten, wie Reparaturmechanismen der Zelle oder Ursachen von Chromosomenver{nderungen, werden angewandte Aspekte, z.B. Chromosomen als Testindikatoren der Toxizit{t, behandelt.
Gunter Umberg
Sir Joseph Dalton Hooker (1817–1911) was one of the most eminent botanists of the later nineteenth century. Educated at Glasgow, he developed his studies of plant life by examining specimens all over the world. After several successful scientific expeditions, first to the Antarctic and later to India, he was appointed to succeed his father as Director of the Botanical Gardens at Kew. Hooker was the first to hear of and support Charles Darwin's theory of natural selection, and over their long friendship the two scientists exchanged many letters. Another close friend was the scientist T. H. Huxley, and it was the latter's son, Leonard (1860–1933), who published this standard biography in 1918. The first volume describes Hooker's early life and his career up to 1860. It includes many letters to Darwin as the two men discussed the new theories and the publication of On the Origin of Species.
Advances in Mutagenesis Research
Applied genetic research, genetic toxicology and mutation research investigate the mutagenicity and cancerogenicity of chemicals and other agents. Permanent mutation in genes and chromosomes, can be induced by aplethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses. Among the aspects discused by Advances in Mutagenesis Research are (1) the understanding of the molecular mechanisms leading to mutations, and (2) the prevention of a thoughtless introduction of mutagenic agents into the environment. Contents: Nikolay W. Timofeeff-Ressovsky (1900-1981): An Essay on his Life and Scientific Achievements. - Arylnitrenium Ions and the Genotoxic Potency of Aromatic A...
Advances in Mutagenesis Research
The new field of applied genetic research, genetic toxicology and mutation research investigates the mutagenicity and cancerogenicity of chemicals and other agents. Permanent changes in genes and chromosomes, or genome mutations, can be induced by a plethora of agents, including ionizing and nonionizing radiations, chemicals, and viruses. Mutagenesis research has two aims: (1) to understand the molecular mechanisms leading to mutations, and (2) to prevent a thoughtless introduction of mutagenic agents into our environment. Both aspects, namely, basic and applied, will be treated in the new series Advances in Mutagenesis Research.
The Bewitching of Anne Gunter
In 1604, 20-year-old Anne Gunter was bewitched: she foamed at the mouth, contorted wildly in her bedchamber, went into trances. Her garters and bodices were perpetually unlacing themselves. Her signature symptom was to vomit pins and "she voided some pins downwards as well by her water or otherwise.." Popular history at its best, "The Bewitching of Anne Gunter" opens a fascinating window onto the past. It's a tale of controlling fathers, willful daughters, nosy neighbors, power relations between peasants and gentry, and village life in early-modern Europe. Above all it's an original and revealing story of one young woman's experience with the greatly misunderstood phenomenon of witchcraft. James Sharpe is Professor of History at York University and the author of "Instruments of Darkness: Witchcraft in" "Early Modern History" and other works of social history.
Fanconi Anemia
This monograph represents the first attempt to gather all aspects of Fanconi's anemia in one source. The editors are well-known for their continuous research in the field and have aptly brought together contributions containing the most up-to-date information available. The difficulties in differential diagnosis and treatment are covered; and the outlook for cure via bone marrow transplantation is included. This overview will interest specialists in human genetics as well as all those dealing with this disease.
Two States--one Nation?
As the Berlin Wall crumbled and the two Germanys became one, Grass was one of a few who spoke out against reunification. In this collection of speeches and debates on the factors destined to reshape Europe, he is caustic, indignant, reflective, and compelling. Translated by Krishna Winston with A. S. Wensinger. A Helen and Kurt Wolff Book
