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Evidence generated by a number of genetic studies indicates that growth is regulated by a number of genes and that interference with their expression can have catastrophic effects on the well being of the whole organism. This work covers skeletal development and growth.
The aim of this book is to outline the physics of image formation, electron specimen interactions and image interpretation in transmission electron mic roscopy. The book evolved from lectures delivered at the University of Munster and is a revised version of the first part of my earlier book Elek tronenmikroskopische Untersuchungs- und Priiparationsmethoden, omitting the part which describes specimen-preparation methods. In the introductory chapter, the different types of electron microscope are compared, the various electron-specimen interactions and their applications are summarized and the most important aspects of high-resolution, analytical and high-voltage electron microscopy are discu...
Extracellular Matrix Influences on Gene Expression emerged from the Second international Santa Catalina Island Colloquium that deals with the discussion on the advances in the molecular biology of extracellular matrices and the epigenetic influences on cell function. Topics discussed include morphological descriptions, genetics, teratology, collagen heterogeneity, and mineralization. The book's 12 chapters discuss the chromosomal and extrachromosomal influences upon transcription, translational and post-translational regulations during development, and regulation of extracellular matrix molecular biosynthesis. The book describes the regulation of tissue-specific collagen biosynthesis and the...
This volume is based in part upon the proceedings of the Calcium Theme held during the 67th Annual Meeting of the Federation of American Societies for Experimental Biology, which took place in Chicago, AprillO-lS, 1983. The American Society for Pharmacology and Experimental Therapeutics had the primary responsibility for organizing the scientific program with the assistance of other member societies, including the American Physiology Society, American Association of Pathologists, and American Institute of Nutrition. The purpose of the Calcium Theme was to review progress in the diverse areas of investigation bearing on the ubiquitous role of calcium in biological systems. In addition to cont...
Nearly two hundred years ago Crawford and Cruickshank, surgeons and chemists in the Royal Artillery, reported the occurrence of a "new earth" in the mines at the Scottish village of Strontian. Humphrey Davy, following the advice of Berzelius, isolated stable strontium in 1808 along with other alkali earth metals. It was not until 1883 that physiological effects of stable strontium were first recognized by none other than Sidney Ringer in his experiments on frog heart. The medicinal use of strontium salts was first described in Squire's Companion in 1894. Subsequently, strontium was introduced into the Pharma copeias of Great Britain, United States, France, Germany, Spain, Italy, and Mexico a...
Combining a reader-friendly textbook and a rich, full-color atlas, Histology: A Text and Atlas: With Correlated Cell and Molecular Biology, 9th Edition, equips medical, dental, health professions, and undergraduate biology and cell biology students with a comprehensive grasp of the clinical and functional correlates of histology and a vivid understanding of the structural and functional details of cells, tissues, and organs. The 9th Edition of this bestselling resource reflects the latest advances in cellular and molecular biology and relevant imaging techniques, accompanied by large, high-resolution illustrations and full-color photomicrographs that clarify microanatomy in vibrant detail. S...