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A summary of current knowledge and unresolved issues Recognition of evidence-based medicine is not only increasing rapidly, but it has become essential to pediatric nutrition. Starting with some methodological issues - discussing systemic reviews, meta-analyses and clinical trials - this publication then concisely summarizes current knowledge as well as ignorance and uncertainty regarding selected aspects of childhood nutrition. These aspects include functional gastrointestinal disorders, issues concerning various kinds of milk, complementary foods, enteral nutrition, celiac disease or obesity. Contents are based on evidence and summarize current guidelines; moreover, when there is no clear evidence, they provide some food for thought. Overall, this publication has been written to enable the clinician to make informed decisions regarding pediatric nutrition.
Adequate nutrition is especially important during infancy and childhood, where even short periods of malnutrition have long-lasting effects on growth, development and health in adult life. There are several high-risk scenarios for the development of malnutrition, which are the focus of the current publication: Atopic diseases, gastrointestinal disorders, and preterm delivery. For the pediatric allergist it is important to understand the mechanisms regulating IgE responses to food proteins since they may also be the earliest markers for the atopic march. As breastfeeding seems to have only limited effects regarding the atopic march, other measures to modulate infantile immune responses have t...
"Growth as an indicator of health is more sensitive than commonly believed and can serve as an early sign of imbalance, before other malfunctions manifest themselves. This title focuses on the challenges of the interaction between nutrition and growth in the pediatric age group." -- Provided by publisher.
Through five editions, and since 1993, Lactic Acid Bacteria: Microbiological and Functional Aspects has provided readers with information on how and why fermentation by lactic acid-producing bacteria improves the shelf life, palatability, and nutritive value of perishable foods and also how these microbes have been used as probiotics for decades. Thoroughly updated (with the current lactobacilli taxonomy) and fully revised, with a rearrangement of chapters into four sections, the Sixth Edition covers new findings on health effects, properties, production and stability of LAB as well as regulatory aspects globally. The new edition also addresses the technological use of LAB in various ferment...
Fully revised new edition highlighting the scientific and clinical advances in the field of developmental origins of health and disease. Explores new understanding of mechanisms such as epigenetics and the role of environmental influences on the fetus. Interventions throughout the lifespan and implications for public health are also covered.
While lactic acid-producing fermentation has long been used to improve the storability, palatability, and nutritive value of perishable foods, only recently have we begun to understand just why it works. Since the publication of the third edition of Lactic Acid Bacteria: Microbiological and Functional Aspects, substantial progress has been made in
This book examines the international picture regarding probiotic food applications, placing a particular emphasis on the legal context and assessment procedures of probiotic health claims in the major markets for these products. Health claim legislation is described and the ways in which manufacturers can ensure compliance are discussed. The book also covers the use of meta-analysis to assess available data, and case examples from various regulatory cultures and traditions are included. It will be of interest to food industry scientists, executives and R&D personnel; international regulatory advisers and administrators; researchers, educators and students on food science courses. Key Features: Focuses on health claim legislation for this commercially important food sector Includes chapters on the current situation in all the major world markets including Europe, the USA, Japan, India and China Covers food, feed and pharmaceutical applications of probiotics
Taking a global approach to the subject, this book offers, in a comprehensive, cohesive package, information that is reflective of the different realities of gastroenterological and nutritional problems in different parts of the world. Designed to provide clinical knowledge in a convenient format, the chapters highlight the most common clinical concerns seen on a daily basis by the practicing pediatric gastroenterologist. Covering issues relevant for the diagnosis and treatment of a full range of problematic conditions, including nutritional disorders, the book is an up-to-date, reliable clinical primer on the disorders and diseases that may affect the gastrointestinal tract in neonates and children.
Probiotics in Pediatric Medicine provides clinicians a tool to understand the current evidence for the role of probiotics in various pediatric disorders related to the gastrointestinal as well as the extra-intestinal tract. This book provides evidence-based up-to-date information from world experts in their fields to help clinicians make decisions regarding the use of probiotics. A list of resources, web sites, and references relevant to probiotics can be found in the appendix. Currently, the market for probiotics continues to rely heavily on health claims made by manufacturers and retailers. Clinicians have the sole responsibility to understand the various strains and preparations commercially available and to advise patients accordingly. Probiotics in Pediatric Medicine is an indispensable tool and a critical resource for health professionals that will aid in enhancing their ability to make the appropriate decisions regarding the use of probiotics.
Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.