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This textbook provides a comprehensive overview of the state of the art knowledge of breast cancer management for the modern breast surgeon. It covers all aspects of multidisciplinary care including primary breast and axillary surgery, reconstruction and oncoplastic techniques, external beam radiotherapy and newer techniques such as tomotherapy, intraoperative radiotherapy and brachytherapy. In addition, systemic therapies including chemotherapy, the latest biological targeted therapies and endocrine therapies are covered. Readers can find out about other important aspects of breast cancer such as genetics, screening, imaging and long-term health among others. Chapters take the reader throug...
Treatment strategies for breast cancer are wide-ranging and often based on a multi-modality approach, depending on the stage and biology of the tumour and the acceptance and tolerance of the patient. They may include surgery, radiotherapy, and systemic therapy (endocrine therapy, chemotherapy, and targeted therapy). Advances in technologies such as oncoplastic surgery, radiation planning and delivery, and genomics, and the development of novel systemic therapy agents alongside their evaluation in ongoing clinical trials continue to strive for improvements in outcomes. In this Special Issue, we publish a collection of studies looking at all forms of therapeutic strategies for early and advanced breast cancer, focusing on their outcomes, notably survival.
Umfassend und praxisorientiert: Ärzte erhalten Anweisungen für diagnostisches Vorgehen, operative Therapie und Strahlentherapie sowie die adjuvante systemische Therapie. Zusätzlich mit den Themen plastische Chirurgie, Pflege und Nachsorge. Mit neuester, Leitlinie, neuem Kapitel zum politischen Stand in der Betreuung, u.a.: Entwicklungen von Diagnose und Therapie, S3-Leitlinie, Zertifizierung von Brustkrebszentren, Disease-Management-Programme.
The Danish author Hans Christian Andersen was a prolific writer of novels, travelogues, poetry and fairy tales. Beloved stories such as ‘The Little Mermaid’, ‘The Snow Queen’, ‘The Ugly Duckling’ and ‘Thumbelina’ are among the most frequently translated works in all literary history. For the first time in publishing history, this comprehensive eBook presents Andersen’s complete fictional works, with numerous illustrations, rare texts, informative introductions and the usual Delphi bonus material. (Version 1) * Beautifully illustrated with images relating to Andersen’s life and works * Concise introductions to the novels and other texts * All 6 novels in English translatio...
Contains Jahresbericht der Gesellschaft für Pommersche Geschichte und Alterthumskunde, no. 5-77, 1829/30-1914/15.
Medizinisches Wissen fundiert und verständlich für die Frau von heute! Sie wollen sich heute selbst über Gesundheit und Krankheit informieren? Medien, Ratgeber und Internet bieten eine Fülle von Informationen. Dennoch stellen sich viele Frauen die Frage: Wie seriös und glaubwürdig sind die Informationsquellen? Das neue Handbuch Gerne Frau! vermittelt aktuelles Wissen und Sicherheit!
Abstract: In patients with existing ovarian function, there are some special aspects to adjuvant endocrine therapy in premenopausal patients with hormone receptor-positive, HER2-negative (HR pos./HER2 neg.) breast cancer. Treatment options include tamoxifen with or without a GnRH analog, and aromatase inhibitors with a GnRH analog. Furthermore, ovarian function is affected by previous chemotherapy. Both aromatase inhibitors (+GnRH analogs) and GnRH analogs in combination with tamoxifen are supposed to be indicated for patients at increased risk of recurrence. However, national and international guidelines and therapy recommendations do not provide a clear definition of intermediate or high r...