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Allergy Matters
In Western societies the incidence and prevalence of respiratory and food-related allergies have increased rapidly over the past decades. Changes in life style are thought to be involved in this increase, namely hygiene, child vaccination, housing insulation and food consumption patterns. This book reflects the current ideas for future possibilities of allergy prevention, using integrated and multidisciplinary strategies and covering the entire knowledge framework from comprehensive fundamental research to implementation into society.
Tropical Diseases
Tropical Diseases: From Molecule to Bedside covers a wide range of topics that reflect perspectives of northern and southern hemispheres. Fittingly, it defines tropical diseases in a broader-than-usual manner. The book discusses traditional tropical medicine topics of infectious diseases and nutritional deficiencies. These diseases are common in the tropics, although some are associated more with poverty than with tropical living conditions. It also deals with genetic diseases and genomic issues that are truly associated with living in the tropics, e.g. the thalassemias. The book begins with several papers describing the vast human genetic diversity of Southeast Asia and its relationship to several genetic disorders. These papers illustrate the future direction of genomic activities in relation to disease susceptibility and resistance. The next sections deal with malaria and four specific viral and bacterial diseases of the tropics: hepatitis B and C, tuberculosis, and leprosy, followed by a section on general bacterial infection. Two papers on nutrition complete the volume.
Chemoreception
Since 1959, the International Society of Arterial Chemoreception (ISAC) has organized in a variety of countries fifteen scientific meetings devoted to the mechanisms of peripheral arterial chemoreception and chemoreceptor reflexes. After the meeting held in Philadelphia with Sukhamay Lahiri as president, ISAC membership elected Lyon (CNRS, University Claude Bernard, France) as the site of the xv" ISAC Symposium. The Symposium was effectively held in Lyon from the 18th to the 22nd of November 2002 and Jean-Marc Pequignot was its president. The organizers were Jean-Marc Pequignot and Yvette Dalmaz Lyon (CNRS, University Claude Bernard, France) and the Scientific Committee was formed by John Ca...
New Trends in Cancer for the 21st Century
Given the latest advances in cancer research, which includes basic research and its derived diagnostic, clinical, and therapeutic applications, the book New Trends in Cancer for the 21st Century is written by individuals such as molecular biologists, whose tasks are to decipher, after sequencing the human genome, those new genes and pathways involved in the carcinogenesis process; clinical and molecular pathologists, who apply these discoveries for the molecular diagnosis and characterization of the tumor; and clinical oncologists, who treat patients. Pharmacogenetics introduces new perspectives in the translational fields with the design of drugs against specific targets, which at this moment are in clinical trials phases. This book achieves a state of the art in every field of cancer research and discusses the new perspectives that will open the future for cancer treatment (basic research, new technologies, new drugs, therapies...). For this reason, the book is intended for pathologists, clinicians, and biologists, as well as fellows and students of physiology and medicine.
Retinal Degenerations
The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
Bioactive Peptides
Bioactive peptides have been receiving attention recently due to their applications as health-promoting agents. Derived from food proteins and other natural sources, they exhibit various beneficial effects such as preventing diseases or modulating physiological systems once absorbed. As the market for nutraceuticals and functional foods continues to expand, consumer interest has also grown and there are many common foods that have shown an abundance of bioactive peptides, including dairy products, cereal, legumes, meat, and numerous other sources. In this newest addition to the series Nutraceuticals: Basic Research and Clinical Applications, Bioactive Peptides: Production, Bioavailability, H...
The International Exhibition of 1862
Replete with detailed engravings, this four-volume catalogue was published to accompany the International Exhibition of 1862. Held in South Kensington from May to November, the exhibition showcased the progress made in a diverse range of crafts, trades and industries since the Great Exhibition of 1851. Over 6 million visitors came to view the wares of more than 28,000 exhibitors from Britain, her empire and beyond. Featuring explanatory notes and covering such fields as mining, engineering, textiles, printing and photography, this remains an instructive resource for social and economic historians. The exhibition's Illustrated Record, its Popular Guide and the industrial department's one-volume Official Catalogue have all been reissued in this series. Volume 4 continues to catalogue the Foreign Division. Notable is the appearance of early exhibits from Steinway et Sons in the brief section for the United States. In contrast, Austrian and German exhibits occupy more than 400 pages.
The Functional Roles of Glial Cells in Health and Disease
Thirty-five years ago, when Stephen Kuffler and his colleagues at Harvard initiated a new era of research on the properties and functions of neuroglial cells, very few neuro scientists were impressed at the time with the hypothesis that neuroglial cells could have another, though more subtle, role to play in the nervous system than to provide static support to neurons. Today, very few neuroscientists are unaware of the fact that multiple interactions between neurons and glial cells have been described, and that they consti tute the basis for understanding the function and the pathology of the nervous system. Glial cells outnumber neurons and make up about one-half of the bulk of the nervous system. They are divided into two major classes: first, the macroglia, which include astrocytes and oligodendrocytes in the central nervous system, and the Schwann cells in the peripheral nervous system; and second, the microglial cells. These different classes of glial cells have different functions and contribute in different ways in the devel opment, function, and the pathology of the nervous system.
