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Meanings of words are constantly changing, and the forces driving these changes are varied and diverse. Linguistic analyses are usually concerned with language-internal processes, while investigations of language-external historical developments tend to disregard linguistic considerations. It is evident, however, that an investigation of diachronic semantics will have to consider both sides: a specific theory of meaning including a proper place for lexical semantics on the one hand, and incorporate knowledge about the world and the social and cultural environment of speakers who use language as a tool for communication on the other. The collection focuses on meaning change as a topic of inte...
The full texts of Armed Services and othr Boards of Contract Appeals decisions on contracts appeals.
Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular response to DNA injury. Given the importance of therapies that induce DNA injury in the management of human disease, this book is timely and relevant for basic and translational researchers, as well as clinicians alike.
From extensive research, including a remarkable interview with the unrepentant chief of Hitler’s Women’s Bureau, this book traces the roles played by women – as followers, victims and resisters – in the rise of Nazism. Originally publishing in 1987, it is an important contribution to the understanding of women’s status, culpability, resistance and victimisation at all levels of German society, and a record of astonishing ironies and paradoxical morality, of compromise and courage, of submission and survival.
In variational linguistics, the concept of space has always been a central issue. However, different research traditions considering space coexisted for a long time separately. Traditional dialectology focused primarily on the diatopic dimension of linguistic variation, whereas in sociolinguistic studies diastratic and diaphasic dimensions were considered. For a long time only very few linguistic investigations tried to combine both research traditions in a two-dimensional design – a desideratum which is meant to be compensated by the contributions of this volume. The articles present findings from empirical studies which take on these different concepts and examine how they relate to one ...
Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.
Robotics began as a science fiction creation which has become quite real, first in assembly line operations such as automobile manufacturing, airplane construction etc. They have now reached such areas as the ever-multiplying - medical field. Robotic surgery is now becoming highly practised in open heart, lung, and other forms of surgery. This book covers the developing stages of robotic surgery and its expectations in the medical field.