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Amorphous Solid Dispersions
  • Language: en
  • Pages: 702

Amorphous Solid Dispersions

  • Type: Book
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  • Published: 2014-11-21
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  • Publisher: Springer

This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characteriz...

Refugee and Humanitarian Admissions
  • Language: en
  • Pages: 662

Refugee and Humanitarian Admissions

  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

None

Becoming an American
  • Language: en
  • Pages: 306

Becoming an American

  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

None

Oversight Hearing on the Columbia River Gorge National Scenic Area Act
  • Language: en
  • Pages: 648
Forum
  • Language: en
  • Pages: 8

Forum

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

None

Legal Admissions
  • Language: en
  • Pages: 288

Legal Admissions

  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

None

Biennial Evaluation Report
  • Language: en
  • Pages: 602

Biennial Evaluation Report

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

None

Staffing the Multilingually Impacted Schools of the 1990s
  • Language: en
  • Pages: 30

Staffing the Multilingually Impacted Schools of the 1990s

  • Type: Book
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  • Published: 1990
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  • Publisher: Unknown

None

Hemlock Dam Fish Passage Evaluation and Restoration
  • Language: en
  • Pages: 210

Hemlock Dam Fish Passage Evaluation and Restoration

  • Type: Book
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  • Published: 1999
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  • Publisher: Unknown

None

Formulating Poorly Water Soluble Drugs
  • Language: en
  • Pages: 656

Formulating Poorly Water Soluble Drugs

This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds. Further, this book is designed to provide practical guidance for overcoming formulation challenges toward the end goal of improving drug therapies with poorly water-soluble drugs. Enhancing solubility via formulation intervention is a unique opportunity in which formulation scientists can enable drug therapies by creating viable medicines from seemingly undeliverable molecules. With the ever increasing number of poorly water-soluble compounds entering development, the role of the formulation scientist is growing in importance. Also, knowledge of the advanced analytical, formulation, and process technologies as well as specific regulatory considerations related to the formulation of these compounds is increasing in value. Ideally, this book will serve as a useful tool in the education of current and future generations of scientists, and in this context contribute toward providing patients with new and better medicines.