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Who are the Jews--a race, a people, a religious group? For over a century, non-Jews and Jews alike have tried to identify who they were--first applying the methods of physical anthropology and more recently of population genetics. In Legacy, Harry Ostrer, a medical geneticist and authority on the genetics of the Jewish people, explores not only the history of these efforts, but also the insights that genetics has provided about the histories of contemporary Jewish people. Much of the book is told through the lives of scientific pioneers. We meet Russian immigrant Maurice Fishberg; Australian Joseph Jacobs, the leading Jewish anthropologist in fin-de-siècle Europe; Chaim Sheba, a colorful Is...
Who are the Jews-- a race, a people, a religious group? Osterer offers readers an entirely fresh perspective on the Jewish people and their history, with a cutting-edge portrait of population genetics, a field which may soon take its place as a pillar of group identity alongside shared spirituality, shared social values, and a shared cultural legacy.
This book addresses the basic mechanisms for the transmission of genetic disorders in humans, and explores the evidence for a number of non-Mendelian genetic processes such as gonadal and somatic mosaicism, sex-linked inheritance, mitochondrial transmission, genomic imprinting, accelerated rates of mutation, and viral infection. In additional to an examination of the molecular basis for these processes and their effects on transmission and phenotype, the authors show how they resolve many of the exceptions to Mendelian inheritance. The book includes a complete review of Mendelian genetics and an overview on the structure and function of genes, chromosomes, and their products. transmission of genetic disorders in humans, stressing such non-Mendelian processes as mitochondrial inheritance, genomic imprinting and dynamic mutation.
Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature—to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why. What is wrong with re-engineering our nature? The Case against Perfection explores these and other moral quandaries connected with the quest to perfect ourselves and our children. Michael Sandel argues that the pursuit of perfection is flawed for reasons that go be...
Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.
How many DNA testing companies will show you how to interpret DNA test results for family history or direct you to instructional materials after you have had your DNA tested? Choose a company based on previous customer satisfaction, and whether the company gives you choices of how many markers you want, various ethnic and geographic databases, and surname projects based on DNA-driven genealogy. Before you select a company to test your DNA, find out how many genetic markers will be tested. For the maternal line, 400 base pairs of sequences are the minimum. For the paternal line (men only) 37 markers are great, but 25 markers also should be useful. Some companies offer a 12-marker test for sur...
Personalized medicine is what this book is about-tailoring your lifestyle, food, medicines, treatments, and reproductive choices to your genetic signature. According to Dr. Andrew Y. Silverman, MD, PhD, "The desire to influence the sex of the next child is probably as old as recorded history." "Gender selection is possible because of the way in which sex is determined by our chromosomes. Dr. Ericsson devised patented methods by which X and Y sperm can be separated through filtering processes. Sperm are "layered" over a column of human serum albumin, and they swim down the gradient where they are collected in the bottom layer. "The fraction of sperm that contains the male (Y) bearing sperm is used for insemination if a boy is desired. It is effective 70?75% of the time. "The fraction of sperm that contains the female (X) bearing sperm is used for insemination if a girl is desired. It is effective 70?72% of the time." Use personalized medicine more effectively. Empower consumers by interpreting DNA testing and learning more about infant gender choice by genetics.
For all the talk about personalized medicine, our health care system remains a top-down, doctor-driven system where individuals are too often bit players in their own health decisions. In The Decision Tree, Thomas Goetz proposes a new strategy for thinking about health, one that applies cutting-edge technology to put us at the center of the equation and explains how the new frontier of health care can impact each of our lives.
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Your DNA, including your ancient ancestry and ethnicity has a lot to do with how your body responds to food, medicine, illness, exercise, and lifestyle, but just how much? And how do you know which DNA kits and gene testing are reliable and recognized? Learning about DNA to understand and improve your health is now interactive and available to the average consumer, not limited to students and teachers, but to anyone else. In the last few years genealogy buffs, parents, and anyone interested in DNA without a science background took an interest in DNA tests rests that reveal deep maternal and paternal ancestry. No science background? Don't worry. There's a DNA summer camp near you, or an educational experience in learning about DNA now available to the average consumer. Educators, scientists, and multimedia producers have teamed up to teach you the wonders of DNA, your genes and your lifestyle. It looks like it's the consumer's job to bring people together through the media and through consumer's watchdog organizations, professional associations, and support groups.