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Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences. This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.
Does the scientific process belong in pastoral counseling? Professional Chaplaincy and Clinical Pastoral Education Should Become More Scientific: Yes and No examines the widespread ambivalence among pastoral caregivers and educators over the growing inclusion of science in pastoral care and counseling methodologies. Twenty-three seasoned professionals in the field give candid and sometimes emotional accounts of their interest in—and reservations about—the role scientific research plays in their profession. Some authors look at the issue from a historical perspective; others voice additional concerns. A few make concrete proposals on how chaplaincy can become more scientific. The result i...
This book becomes an invaluable reference on the genetic resources, genome, genes, chemical compounds, and their therapeutic effects for the Lingzhi mushrooms. It is the first comprehensive compilation of genetic resources, nuclear genome, mitochondrial genome, genes, noncoding RNAs, such as long intergenic noncoding RNAs, microRNAs, circular RNAs, genes in the biosynthetic pathway, chemical compounds and their therapeutic effects, transformation system for the expression of key genes, a bibliometric analysis to identify the past research work and the future research direction, and a survey of products derived from the Lingzhi mushrooms. Each chapter of this book is written by authors of glo...
There are only few discoveries and new technologies in physical sciences that have the potential to dramatically alter and revolutionize our electronic world. Topological insulators are one of them. The present book for the first time provides a full overview and in-depth knowledge about this hot topic in materials science and condensed matter physics. Techniques such as angle-resolved photoemission spectrometry (ARPES), advanced solid-state Nuclear Magnetic Resonance (NMR) or scanning-tunnel microscopy (STM) together with key principles of topological insulators such as spin-locked electronic states, the Dirac point, quantum Hall effects and Majorana fermions are illuminated in individual chapters and are described in a clear and logical form. Written by an international team of experts, many of them directly involved in the very first discovery of topological insulators, the book provides the readers with the knowledge they need to understand the electronic behavior of these unique materials. Being more than a reference work, this book is essential for newcomers and advanced researchers working in the field of topological insulators.
Dangerous, dark and difficult to detect, poisons have been a common character in literature from ancient times to the modern day. Their ability to perform deadly deeds at a distance is a common device for creating dramatic tension and playing on our real life fears. But what is fact and what is pure fiction? From Shakespeare and Dickens to Hugo and Poe, the macabre world of literary poisonings is as large as it is fascinating. Utilising real forensic science Poisonous Tales explores the real science inspiring the toxins and tinctures in our favourite works. Could a poison really mimic death in Romeo and Juliet? What is the cause of the mad Hatter's malady in Alice in Wonderland? And could a stone from the stomach of a goat really have been used as an antidote in Harry Potter and the Half-Blood Prince? Through these and many more 'cases' we discover the captivating truth in the texts and how real-life tragedies can replicate themselves in fiction.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This volume offers a comprehensive account of language development from a Systemic Functional Linguistic (SFL) perspective, integrating theory and data from a wide range of research studies. The book begins by taking an in-depth look at SFL theory and its focus on texts, highlighting the metafunctional nature of language and the ways in which individuals’ repertoires of meaning-making resources develop as they interact with the world and with others. Grounded in an SFL approach, the successive chapters consider in turn the key stages of language development, from infancy to school settings to additional, second, and foreign language learning contexts. Each chapter incorporates a range of S...
This single-volume reference covers the natural course, treatment, and management of all neurological diseases affecting the brain, spinal cord nerves and muscles. This comprehensive text reference seeks to assist physicians with treatment by providing an easy-to-use compendium covering the treatment and management of all neurological diseases along with details on the natural course of these diseases. Organized for ease of use and quick reference, each chapter presents a neurological disorder or key symptoms and systematically discusses the clinical syndrome and differential diagnosis, natural course, principles of therapy, and practical management of each. Covers wide range of neurological conditions and potential treatments, including the evidence for and against each treatment Describes the spontaneous course of neurological diseases along with discussion of the management of different stages and variants of a disorder Presents special situations and exceptional cases in which alternative therapies should be considered