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Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development
Written by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner. The book starts by describing the motivation and the urgent need for the implementation of the QbD framework in pharmaceutical development, along with the definition of its major elements: Quality Target Product Profile (QTTP), Critical Quality Attributes (CQAs), Critical Process Parameters (CPPs), Critical Material Attributes (CMAs) and the importance of using multivariate methods of Design of Experiments (DOE). The concept of life cycle...
Fundamentals and Applications of Multiway Data Analysis
Fundamentals and Applications of Multiway Data Analysis provides comprehensive coverage of the main aspects of multiway analysis, including selected applications that can resolve complex analytical chemistry problems. This book follows on from Fundamentals and Analytical Applications of Multiway Calibration, (2015) by addressing new theoretical analysis and applications on subjects beyond multiway calibration and devoted to the analysis of multiway data for other purposes. Specifically, this new volume presents researchers a set of effective tools they can use to obtain the maximum information from instrumental data. This book includes the most advanced techniques, methods and algorithms rel...
Nanobiotechnology for Sustainable Food Management
Among the most novel and ever-growing approaches to improving the food industry is nanobiotechnology. In this book, the prospective role of nanobiotechnology in food which includes quality control and safety through nanosensors and biosensors, targeted delivery of nutrients, controlled release of nutrients, proteins, antioxidants, and flavors through encapsulation and enzymatic reactions for food fortification of fat-soluble compounds is discussed. Along the chapters of this book, nanobiotechnological techniques are addressed in detail with specific emphasis on food science applications. Features: Discusses nanobiotechnology in food for quality control and safety Covers food processing and packaging for food safety Explores the positive role of nanomaterials towards the sustainability of food Provides efficient, real, and sustainable solutions to pertinent global problems Includes case studies and research directions of the nanobiotechnology This book is aimed at researchers and graduate students in nanotechnology and food engineering.
Chemical Sensors
Chemical sensors contain two basic functions: recognition and transduction, and provide real-time information about substances rather than physical quantities. Such devices are extensively utilized for various applications in diverse fields. The book focuses on the physical, chemical, optical, and electrical working mechanisms of different types of sensors integrated with various smart nanomaterials and composites. The mesmerizing properties of numerous materials and their fruitful applications for detecting numerous chemical parameters are discussed here. The book provides recent progress in the chemical sensors field and connects materials, physics, chemistry, and engineering, and therefore, is suitable for engineers, industrial, and academic researchers.
Proceedings of the 5th International Symposium on Uncertainty Quantification and Stochastic Modelling
This proceedings book discusses state-of-the-art research on uncertainty quantification in mechanical engineering, including statistical data concerning the entries and parameters of a system to produce statistical data on the outputs of the system. It is based on papers presented at Uncertainties 2020, a workshop organized on behalf of the Scientific Committee on Uncertainty in Mechanics (Mécanique et Incertain) of the AFM (French Society of Mechanical Sciences), the Scientific Committee on Stochastic Modeling and Uncertainty Quantification of the ABCM (Brazilian Society of Mechanical Sciences) and the SBMAC (Brazilian Society of Applied Mathematics).
Fundamentals and Analytical Applications of Multiway Calibration
Fundamentals and Analytical Applications of Multi-Way Calibration presents researchers with a set of effective tools they can use to obtain the maximum information from instrumental data. It includes the most advanced techniques, methods, and algorithms related to multi-way calibration and the ways they can be applied to solve actual analytical problems. This book provides a comprehensive coverage of the main aspects of multi-way analysis, including fundamentals and selected applications of chemometrics that can resolve complex analytical chemistry problems through the use of multi-way calibration. Includes the most advanced techniques, methods, and algorithms related to multi-way calibration and the ways they can be applied to solve actual analytical problems Presents researchers with a set of effective tools they can use to obtain the maximum information from instrumental data Provides comprehensive coverage of the main aspects of multi-way analysis, including fundamentals and selected applications of chemometrics
Liquid Chromatography
Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceutica...
Fingerprinting Techniques in Food Authentication and Traceability
There is an increasing interest by consumers for high-quality food products with a clear geographical origin. With these products in demand, suitable analytical techniques are needed for the quality control. Current analytical approaches are mass spectrometry techniques, spectroscopic techniques, separation techniques, and others. Fingerprinting Techniques in Food Authentication and Traceability discusses the principles of the techniques together with their advantages and drawbacks, and reported applications concerning geographical authenticity. A combination of methods analyzing different types of food compounds seems to be the most promising approach to establish the geographical origin. T...
Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009
The 21st ESACT conference was held in the beautiful surroundings of the CityWest Hotel resort in Dublin, Ireland. For the first time in ESACT history the number of participants exceeded 900: a sign of the ever increasing importance of this area. The conference commenced on Sunday June 5th with two sets of parallel workshops on the subjects listed below. An additional workshop was held on Monday lunchtime of the conferenceProcess Analytical Technology (PAT), Quality by Design (QbD) and other recent regulatory developments. 2. Innovative media products for the 21st century biopharmaceutical industry. 3. The impact of high titre media feed-streams on monoclonal antibody purification. 4. Advances in genomics and proteomics. 5. Stem Cell Technology: new developments and clinical applications.
Proceedings of the 6th International Symposium on Uncertainty Quantification and Stochastic Modelling
This proceedings book covers a wide range of topics related to uncertainty analysis and its application in various fields of engineering and science. It explores uncertainties in numerical simulations for soil liquefaction potential, the toughness properties of construction materials, experimental tests on cyclic liquefaction potential, and the estimation of geotechnical engineering properties for aerogenerator foundation design. Additionally, the book delves into uncertainties in concrete compressive strength, bio-inspired shape optimization using isogeometric analysis, stochastic damping in rotordynamics, and the hygro-thermal properties of raw earth building materials. It also addresses d...
