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Leishmaniasis: From Innate and Adaptive Immunity to Vaccine Development
The parasitic disease leishmaniasis in its various clinical manifestations from self-resolving skin lesion to deadly systemic infection is a serious health problem in many developing countries and is considered to be a neglected tropical disease by the World Health Organization. To date, a vaccine is lacking and strategies to treat severe forms of leishmaniasis efficiently are missing. Basic research using animal models of experimental visceral or cutaneous leishmaniasis has allowed to dissect the immune response to parasitic pathogens and has contributed substantially to many important, paradigm-changing insights such as the role of cytokines in helper T-cell differentiation and the impact ...
Fables of the Popes in the Middle Ages
Reprint of the original, first published in 1872. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.
Antiphospholipid Antibodies and Syndrome
This book is a printed edition of the Special Issue "Antiphospholipid Antibodies and Syndrome" that was published in Antibodies
Molecular Parasitology
In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.
Parasites in the Tropic - A New Paradigm Shift
The highlight of this eBook is to bring new insights into parasites in the tropic. To achieve that, much has been discussed about risk assessment, infection rates, disease burden, hormones and mechanism of immune response, genetic expression and susceptibility as well as, therapeutic modalities. Authors raised hypothesis, discuss concepts, and show open questions. The remaining important issues to resolve questions within parasites in the tropic – a new paradigm shift are briefly discussed below. T. gondii, feline as the definitive host, is regarded as one of the most important parasites in the tropic. Human, as an accidental host, is the only species who still drinks raw milk or milk prod...
Ganoderma
Ganoderma holds significant traditional importance in various ethnic cultures around the world, particularly in China, Japan, and Korea. Many indigenous traditions have incorporated Ganoderma into medicinal practices, being considered a symbol of longevity, vitality, and good health. At present, the taxon is believed to possess various health benefits and is used to treat ailments and promote overall well-being. In this context, the first volume of the book, titled Ganoderma: Cultivation, Chemistry and Medicinal Applications, aims to comprehensively cover the taxonomy, morphological features, domestication strategies, structures of secondary metabolites, and therapeutic prospects of Ganoderm...
Immune evasion strategies in protozoan-host interactions
The protozoa are the most ancient members of the animal kingdom and they have evolved the intracellular parasitism to ensure their survival strategies. Protozoan parasites that infect humans are extremely diverse among eukaryotes. They are responsible for many human diseases such as amebiasis, Chagas disease, malaria, toxoplasmosis, leishmaniasis and African sleeping sickness. The ability of protozoans to cause disease depends on the nature and number of infecting organisms, the route of infection, the virulence factors associated with the microorganism, and the strength of host defenses. This host-parasite interaction is also subject to constant change as the infection proceeds and can lead...
