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Producing, sensing and responding to cellular stress in immunity
Cellular stress, being considered as any disturbance in cellular physiology, is a fundamental aspect of tissue and body capacity to adapt to the ever changing environment. It also surges as a consequence of tissue injury or invasion of the body by pathogens. Since the immune system was developed to sense and respond to these deleterious processes, it is reasonable to consider that immune cells are capable of sensing and responding to signs of cellular stress. Moreover, cells of the immune system undergo cellular stress during an immune response. This Research Topic presents a series of articles focusing on how cellular stress influences the outcome of immune responses, covering not only how cellular stress can be a fundamental process during immune cell activation and function, but also how cells of the immune system are capable of sensing and being influenced by factors produced by stressed cells.
Immunomodulatory Functions of Nutritional Ingredients in Health and Disease
Nutritional immunology is a rapidly developing field. An expanding body of evidence demonstrates the impact of foods and nutritional components on gut and systemic immunity of consumers. During recent years, the implications of nutrition and nutritional intervention on prevention of disease have become accepted and has become an important tool in management of several diseases. Nutritional immunology might become even more important in the prevention of disease when the interplay between nutritional processes and immune system is better understood. Particularly, specific cellular and molecular immune responses provoked by nutrition and the role of the gut barrier and microbiota in the interplay needs more study. This content of eBook was designed to provide a timely collection on mechanistic, translational and clinical research on the interplay between foods, nutritional components and immunity in physiological and pathophysiological conditions.
The Role of Cytosolic Sensors in Host Defense to Intracellular Pathogens
Innate immunity is the first arm of the immune system to be triggered in host defense against intracellular pathogens. Some pathogens during evolution have developed stealthy strategies to bypass innate surface receptors but when they reach host cell cytosol they are recognized by cytosolic receptors. Professional phagocytes, such as macrophages, neutrophils, or dendritic cells, have the specialized ability to internalize pathogens into membrane-bound compartments, termed phagosomes. Additionally, pathogen phagocytosis effectively guarantees the concentrated delivery of pathogen-associated molecular patterns (PAMPs) inside cells. Some pathogens can exit phagosomes and survive and replicate i...
Understanding Obesity
Most people have some dissatisfaction or concern about body weight, fatness, or obesity, either personally or professionally. This book shows how the popular understanding of obesity is often at odds with scientific understandings, and how misunderstandings about people with obesity can further contribute to the problem. It describes, in an approachable way, interconnected debates about obesity in public policy, medicine and public health, and how media and social media engage people in everyday life in those debates. In chapters considering body fat and fatness, genetics, metabolism, food and eating, inequality, blame and stigma, and physical activity, this book brings separate domains of obesity research into the field of complexity. By doing so, it aids navigation through the minefield of misunderstandings about body weight, fatness, and obesity that exist today, after decades of mostly failed policies and interventions.
Neutrophil Methods and Protocols
This book provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Scientists and clinicians will find this collection an invaluable aid.
The Zebrafish
The zebrafish (Danio rerio) is a valuable and common model for researchers working in the fields of genetics, oncology and developmental sciences. This full-color atlas will aid experimental design and interpretation in these areas by providing a fundamental understanding of zebrafish anatomy. Over 150 photomicrographs are included and can be used for direct comparison with histological slides, allowing quick and accurate identification of the anatomic structures of interest. Hematoxylin and eosin stained longitudinal and transverse sections demonstrate gross anatomic relationships and illustrate the microscopic anatomy of major organs. Unlike much of the current literature, this book is focused exclusively on the zebrafish, eliminating the need for researchers to exclude structures that are only found in other fish.
Brazilian Crops in the Global Market
This book comprehensively examines the development of Brazilian agriculture by focusing on the crops which evolved from national products to international commodities on a massive scale. It traces the transformation of Brazil from a country with low-yield levels in 1950 to its current position as a leading world producer. The first section of the book examines the modernization of Brazilian agriculture through a government programme which transformed traditional agriculture through subsidized credit, guaranteed prices, stock purchases, land utilization laws, modern research, new technology and major support for exports. It also explores the changing structures of agricultural production and ...
Do tabuleiro de arroz-doce à Magistratura
Cidadão rondoniense, nasceu em 23 de janeiro de 1940, em um seringal denominado "Prosperidade", à margem esquerda do rio Madeira. Ficou órfão de pai aos dois anos e teve que enfrentar as dificuldades e privações que a vida lhe impôs. Cresceu em meio a uma família de muitos irmãos, uma mãe austera que não gostava de carinho. Aprendeu cedo a se virar. Ajudava a mãe a carregar as trouxas de roupa e as panelas com mingau no tabuleiro de arroz com quitutes que a mãe, à noite, vendia frente aos inferninhos de Porto Velho. Mas, era um menino decidido e dado o nome do local onde nasceu "Prosperidade", estabeleceu uma meta na vida: de que iria sempre prosperar na vida. Foi o que fez da ...
Operations Management for Social Good
This volume showcases the presentations and discussions delivered at the 2018 POMS International Conference in Rio. Through a collection of selected papers, it is possible to review the impact and application of operations management for social good, with contributions across a wide range of topics, including: humanitarian operations and crisis management, healthcare operations management, sustainable operations, artificial intelligence and data analytics in operations, product innovation and technology in operations management, marketing and operations management, service operations and servitization, logistics and supply chain management, resilience and risk in operations, defense, and tourism among other emerging Operations Management issues. The Production and Operations Management Society (POMS) is one of the most important and influential societies in the subject of Production Engineering and, as an international professional and academic organization, represents the interests of professionals and academics in production management and operations around the world.
