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Metabolic Profiling
This volume explores the different approaches and techniques used by researchers to study the recent challenges and developments in metabolic profiling. This book is divided into IV parts. Part I contains chapters that highlight basic concepts, such as experimental design, data treatment, metabolite identification, and harmonization. Part II describes experimental protocols for both targeted and untargeted metabolomics covering the basic analytical technologies: LC-MS, GC-MS, NMR and CE-MS. In addition the protocols describe methods for the study of tissues, feces, blood and other types of biological samples as well as the application of chemical derivatization for GC-MS. Parts III and IV pr...
Chromatographic Methods in Metabolomics
Metabolomics is an emerging field and this is the first book to present chromatographic techniques in metabolomics in a fundamental way.
UHPLC in Life Sciences
Since its commercial introduction in 2004, UHPLC (Ultra-High Performance Liquid Chromatography) has begun to replace conventional HPLC in academia and industry and interest in this technique continues to grow. Both the increases in speed and resolution make this an attractive method; particularly to the life sciences and more than 1500 papers have been written on this strongly-evolving topic to date. This book provides a solid background on how to work with UHPLC and its application to the life sciences. The first part of the book covers the basics of this approach and the specifics of a UHPLC system, providing the reader with a solid background to working properly with such a system. The se...
Proteomic and Metabolomic Approaches to Biomarker Discovery
Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition...
Metabolomics in Practice
Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the insight and advice offered here helps to clear the hurdles in setting up and running a successful analysis, resulting in high-quality data from every experiment. Based on more than a decade of practical experience in developing, optimizing and validating metabolomics approaches as a routine technol...
Fundamentals of Advanced Omics Technologies: From Genes to Metabolites
Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, rec...
Primary Liver Cancer
"Primary Liver Cancer: Challenges and Perspectives" presents the recent progress in basic and clinical research in Primary Liver Cancer (PLC) in China and around the world. PLC patients in China make up more than 50% of the total patients worldwide. By contributing to the book, the leading experts in the field of liver cancer in China as well as in the US share with readers their new concepts, practices, and experiences from bench to bed, from population study to individual survey, from molecular search to clinical practice, and from early diagnosis to treatment. The book is intended for researchers in the fields of epidemiology, molecular genetics, cell biology, immunology of HCC and other cancers, and clinical oncology in primary liver cancer. Jianren Gu is a Professor of molecular oncology at the Shanghai Cancer Institute, Shanghai Jiao Tong University School of Medicine and Academician of Chinese Academy of Engineering.
Ranking of researchers and scientists in Greece in 2017 according to Google Scholar database
Scope: The classification of researchers and scientists in Greece in a unified list based on the citation impact and dissemination level of their scientific work according to Google Scholar database. Classification criteria: First criterion is h-index. In the case of equal h-index, the following scientometric indicators are used for the classification. The number of total citations, the i10-index, the total impact factor of scientist, the m-index or m-quotient of scientist. Information resource: The h-index, citations and i10-index derived from the public profiles of researchers in the Google Scholar database. In addition, the calculation of total impact factor and m-index of each researcher...
Metabolic Profiling
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Molecular Aspects of Alcohol and Nutrition
Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body. The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins. This book explores both the primary and se...
