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Surface Structures of Microorganisms and Their Interactions with the Mammalian Host
  • Language: en
  • Pages: 286

Surface Structures of Microorganisms and Their Interactions with the Mammalian Host

Surface Structures of Microorganisms and Their Interactions with the Mammalian Host Edited by E. Schrinner, M. H. Richmond, G. Seibert, U. Schwarz This book discusses the interactions that occur between the surface layers of microorganisms and the mammalian "host". Particular emphasis is placed on the field of microbial infection and pathogenicity, whereby yeasts, fungi and protozoa are considered in addition to bacteria. Other topics treated include bacterial endotoxins and cell wall degradation products. The twenty contributions to this book were written by a wide range of specialists from different countries. They offer an international and interdisciplinary compilation of current knowledge in this field.

Anticarbohydrate Antibodies
  • Language: en
  • Pages: 445

Anticarbohydrate Antibodies

Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vaccines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to ...

Chlamydia pneumoniae and Chronic Diseases
  • Language: en
  • Pages: 228

Chlamydia pneumoniae and Chronic Diseases

International specialists in Microbiology, Infectious Diseases, Internal Medicine, Cardiology Immunology, Pneumonology, Neurology and Epidemiology gathered to this workshop to discuss and enhance interdisciplinary knowledge on the possible etiological role of Chlamydia pneumoniae, a widespread human respiratory infection, in the pathogenesis of chronic inflammatory diseases with major public health impact such as atherosclerosis, cardiovascular disease, adult-onset asthma bronchiale, chronic obstructive pulmonary diseases, reactive arthritis, morbus Alzheimer and multiple sclerosis. Current deficits and goals in the standardisation of diagnostic tools, basic and applied research, design of epidemiological and monitoring of therapy studies were identified. A special feature of this book is the comprehensive collection of state-of-the-art review articles in the various fields with many references.

Endotoxins: Structure, Function and Recognition
  • Language: en
  • Pages: 419

Endotoxins: Structure, Function and Recognition

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases. The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

The Narrow Edge
  • Language: en
  • Pages: 304

The Narrow Edge

Thousands of ravenous tiny shorebirds race along the water’s edge of Delaware Bay, feasting on pin-sized horseshoe-crab eggs. Fueled by millions of eggs, the migrating red knots fly on. When they arrive at last in their arctic breeding grounds, they will have completed a near-miraculous 9,000-mile journey that began in Tierra del Fuego. Deborah Cramer followed these knots, whose numbers have declined by 75 percent, on their extraordinary odyssey from one end of the earth to the other—from an isolated beach at the tip of South America all the way to the icy tundra. In her firsthand account, she explores how diminishing a single stopover can compromise the birds' entire journey, and how th...

Advances in Carbohydrate Chemistry and Biochemistry
  • Language: en
  • Pages: 407

Advances in Carbohydrate Chemistry and Biochemistry

  • Type: Book
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  • Published: 2006-07-17
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  • Publisher: Elsevier

Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.High quality comprehensive reviews covering all aspects of carbohydrate chemistry

Bacterial Endotoxic Lipopolysaccharides
  • Language: en
  • Pages: 474

Bacterial Endotoxic Lipopolysaccharides

  • Type: Book
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  • Published: 1992-08-05
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  • Publisher: CRC Press

Bacterial Endotoxic Lipopolysaccharides provides an up-to-date, two-volume review of the latest information regarding bacterial lipopolysaccharide structure and activities. These volumes cover the biochemistry, pharmacology, and pathophysiologic properties of endotoxins. The volumes also thoroughly discuss the strengths and weaknesses of new therapies for septic shock that are based on an immunological attack on endotoxins and the cytokines induced by endotoxins. All scientists involved in endotoxin research, clinical infectious disease specialists, and medical students interested in the pathogenesis of septic shock will find Bacterial Endotoxic Lipopolysaccharides invaluable as a reference resource.

Meggs' History of Graphic Design
  • Language: en
  • Pages: 2071

Meggs' History of Graphic Design

Note from the publisher: The Interactive Resource Center is an online learning environment where instructors and students can access the tools they need to make efficient use of their time, while reinforcing and assessing their understanding of key concepts for successful understanding of the course. An access card with redemption code for the online Interactive Resource Center is included with all new, print copies or can be purchased separately. (***If you rent or purchase a used book with an access code, the access code may have been redeemed previously and you may have to purchase a new access code - ISBN: 9781118922248). The online Interactive Resource Center contains resources tied to ...

Immunological Adjuvants and Vaccines
  • Language: en
  • Pages: 245

Immunological Adjuvants and Vaccines

Vaccination, chiefly responsible for the eradication of smallpox and the control of poliomyelitis and German measles in man and of foot-and mouth, Marek's and Newcastle disease in domestic animals, remains the best answer to infectious diseases. Early vaccines were live wild type organ isms but these have been largely replaced by attenuated or killed organisms or by purified components (subunits) thereof. More recently, developments in recombinant DNA techniques, the advent of monoclonal antibodies and progress in our understanding of the immunological structure of proteins, have laid the foundations for a new generation of vaccines. For instance, subuni t vaccines have been produced through...