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Neuromodulation Using Spatiotemporally Complex Patterns
Recent studies have highlighted that stimulation of the nervous system with spatiotemporal patterns may engage the nervous system in fundamentally different ways than can be achieved with conventional single-frequency stimulation. Coordinated Reset deep brain stimulation (DBS) may affect synaptic plasticity and result in long-lasting (after stimulation is turned off) effects. Spatio-temporal paired pulse stimulation can be used to induce spike timing dependent strengthening or weakening of synaptic connections between brain regions for therapeutic purposes. Burst stimulation may enable cell-type specific targeting, as recently shown in rodent models of DBS for Parkinson’s Disease and in thalamic DBS in humans. Burst stimulation has also shown promise in spinal cord for chronic pain and vagus nerve stimulation for cardiac applications. And multiple hierarchies of temporal patterning may have their own unique effect on the nervous system as evidenced by data on intermittent theta-burst transcranial magnetic stimulation for the control of depression.
Applications of Computational Intelligence in Biology
Computational Intelligence (CI) has been a tremendously active area of - search for the past decade or so. There are many successful applications of CI in many sub elds of biology, including bioinformatics, computational - nomics, protein structure prediction, or neuronal systems modeling and an- ysis. However, there still are many open problems in biology that are in d- perate need of advanced and e cient computational methodologies to deal with tremendous amounts of data that those problems are plagued by. - fortunately, biology researchers are very often unaware of the abundance of computational techniques that they could put to use to help them analyze and understand the data underlying ...
Physical Review
Publishes papers that report results of research in statistical physics, plasmas, fluids, and related interdisciplinary topics. There are sections on (1) methods of statistical physics, (2) classical fluids, (3) liquid crystals, (4) diffusion-limited aggregation, and dendritic growth, (5) biological physics, (6) plasma physics, (7) physics of beams, (8) classical physics, including nonlinear media, and (9) computational physics.
Observed Brain Dynamics
The biomedical sciences have recently undergone revolutionary change, due to the ability to digitize and store large data sets. In neuroscience, the data sources include measurements of neural activity measured using electrode arrays, EEG and MEG, brain imaging data from PET, fMRI, and optical imaging methods. Analysis, visualization, and management of these time series data sets is a growing field of research that has become increasingly important both for experimentalists and theorists interested in brain function. Written by investigators who have played an important role in developing the subject and in its pedagogical exposition, the current volume addresses the need for a textbook in t...
The Physics of Complex Systems
This volume focuses on the area of the physics of complex systems and provides both an overview of the field and more detailed examination of those topics within the field that are currently of greatest interest to researchers. The properties of complex systems play an important role in a variety of different and overlapping areas in physics, chemistry, biology, mathematics and technology. The research field of complex systems is very broad, but this volume attempts to be comprehensive. This book is a useful reference work for researchers in this area, whether graduate students or advanced academics. Up-to-date reviews of cutting-edge topics are provided, compiled by leading authorities and ...
The Strange Order Of Things
'Damasio undertakes nothing less than a reconstruction of the natural history of the universe ... [A] brave and honest book' The New York Times Book Review The Strange Order of Things is a pathbreaking investigation into homeostasis, the condition of that regulates human physiology within the range that makes possible not only survival but also the flourishing of life. Antonio Damasio makes clear that we descend biologically, psychologically and even socially from a long lineage that begins with single living cells; that our minds and cultures are linked by an invisible thread to the ways and means of ancient unicellular existence and other primitive life-forms; and that inherent in our very chemistry is a powerful force, a striving toward life maintenance that governs life in all its guises, including the development of genes that help regulate and transmit life. The Strange Order of Things is a landmark reflection that spans the biological and social sciences, offering a new way of understanding the origins of life, feeling and culture.
