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Ambition and Delight
Henry Bournes scientific career spanned four decades of rapidly expanding progress in experimental biology, accelerated by the DNA revolution of the 1980s. Ambition and Delight shows how the unique personalities, joys, and sorrows of individual scientists shape their science. Their discoveries are driven by warm cooperation and painful competition, combined with the viscerally satisfying delight of solving natures puzzles.
Ambition and Delight
Henry Bourne's scientific career spanned four decades of rapidly expanding progress in experimental biology, accelerated by the DNA revolution of the 1980s. Ambition and Delight shows how the unique personalities, joys, and sorrows of individual scientists shape their science. Their discoveries are driven by warm cooperation and painful competition, combined with the viscerally satisfying delight of solving nature's puzzles.
Follow the Money: Funding Research in a Large Academic Health Center
Threatened by sharp cuts in state government support and stagnant federal research funding, US public research universities are becoming fragile ecosystems. By charting flows of research dollars through a leading public research university-the University of California, San Francisco (UCSF)-this book illuminates how such schools work to cope with these funding threats and how the challenges and coping strategies affect organization and direction of research. Academic leaders, faculty, administrators, and students will learn how a complex academic health center manages its revenues, expenses, and diverse academic cultures. For the first time, they can begin to understand arcane mysteries of indirect cost recovery, sponsored funds, capital investment, endowments, debt, and researchers' salaries.
The Prostaglandins
There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E se...
