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Pharmaceutical Biotechnology
This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.
Genetic Modification of Plants
Conceived with the aim of sorting fact from fiction over genetically modified (GM) crops, this book brings together the knowledge of 30 specialists in the field of transgenic plants. It covers the generation and detection of these plants as well as the genetic traits conferred on transgenic plants. In addition, the book looks at a wide variety of crops, ornamental plants and tree species that are subject to genetic modifications, assessing the risks involved in genetic modification as well as the potential economic benefits of the technology in specific cases. The book’s structure, with fully cross-referenced chapters, gives readers a quick access to specific topics, whether that is comprehensive data on particular species of ornamentals, or coverage of the socioeconomic implications of GM technology. With an increasing demand for bioenergy, and the necessary higher yields relying on wider genetic variation, this book supplies all the technical details required to move forward to a new era in agriculture.
The Ubiquitous Roles of Cytochrome P450 Proteins
Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close cooperation with John Wiley & Sons launch a new Series “Metal Ions in Life Sciences”. There exists a whole range of books on Cytochromes P450, but none with the focus of this volume. This new volume in the Series concentrates on current hot topics in the area and tries to work out the underlying common developments. As a result the reader will find a systematic account of new results in this exciting research area. The table of contents gives an idea on the wide span of chapters, starting with overviews and the presentation of specific systems, and ending with chapters on carbon-carbon bond cleavage by P450 sytems, drug metabolism as catalyzed by P450 systems, decomposition of xenobiotics by P450 enzymes and design and engineering of new P450 systems.
Frontiers in Plant Science: 2020 Highlights
The Editorial Office of Frontiers in Plant Science would like to thank all the Chief Editors, Associate Editors and Review Editors that played an integral part in Frontiers’ innovative Collaborative Peer-Review process in 2020. In particular, we would like to recognize and thank Prof. Joshua L. Heazlewood – our now former Field Chief Editor, for his commitment, support and enthusiasm for the Plant Science field. Josh’s dedication and leadership has helped Frontiers in Plant Science become the most cited journal in the field with a strong editorial community. Looking forward, we’re excited to welcome Prof. Yunde Zhao, as our new Field Chief Editor in 2021. Having been with Frontiers in Plant Science since 2017, Yunde has contributed extensively to the development of the journal and will continue to ensure the journal goes from strength to strength.
Medicinal Plant Biotechnology
Covering the latest advances in the use of plants to produce medicinal drugs and vaccines, examines topics including plant tissue culture, secondary metabolite production, metabolomics and metabolic engineering, bioinformatics, molecular farming and future biotechnological directions.
PHARAMACEUTICAL BIOTECHNOLOGY
Pharmaceuticals and biopharmaceuticals are the backbone of modern medicinal therapy. Most traditional pharmaceuticals are low molecular mass organic chemicals. Although some were originally isolated from biological sources, most of them are manufactured by direct chemical synthesis. Two types of manufacturing companies, thus comprise the traditional pharmaceutical sector the chemical synthesis plants, which manufacture the raw chemical ingredients in bulk quantities and the finished product pharmaceutical facilities, which purchase the raw bulk ingredients, formulate them into final pharmaceutical products and supply these products to users. Some products are formed by biological materials which are generally categorized as biotechnological products (hormones, blood products, vaccines). Some bio-products are modified by chemical synthesis which are called semi synthetic drugs.
The Global Governance of Genetic Resources
Multi-institutional governance architectures are increasingly common in world politics, yet how do they evolve over time? This book develops a fresh conceptual approach by distinguishing two main types of institutional change and by proposing the strategic context within which governments make decisions regarding international cooperation as the main driving factor. Applying this theoretical framework to the case of genetic resources, it shows how the scope for change has persistently been circumscribed by asymmetries in the global biotechnology sector. Taking a broad view of the underlying technological, legal and economic factors, the book analyzes the formation of international regimes li...
Metabolons and Supramolecular Enzyme Assemblies
Metabolons and Supramolecular Enzyme Assemblies, Volume 617 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Dynamic plant metabolons, TCA cycle metabolons, the Chemotactic assembly of metabolons, Repurposing peroxisomes for metabolic engineering, Repurposing yeast mitochondria for metabolic engineering, Repurposing plant compartments for metabolic engineering, Protein scaffolds for pathway co-localization on lipid droplets, Engineered enzyme assemblies for metabolic engineering, NRPS assembly lines and P450 interactions, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in this series on enzymology - Updated release includes the latest information on dynamic plant metabolons, TCA cycle metabolons, the chemotactic assembly of metabolons, and much more
Encyclopedia of Plant and Crop Science (Print)
Encyclopedia of Plant and Crop Science is the first-ever single-source reference work to inclusively cover classic and modern studies in plant biology in conjunction with research, applications, and innovations in crop science and agriculture. From the fundamentals of plant growth and reproduction to developments in agronomy and agricultural science, the encyclopedia's authoritative content nurtures communication between these academically distinct yet intrinsically related fields-offering a spread of clear, descriptive, and concise entries to optimally serve scientists, agriculturalists, policy makers, students, and the general public. ALSO AVAILABLE ONLINE This Taylor & Francis encyclopedi...
DNA Technology
This accessibly written book introduces readers to DNA—one of the most important technologies for the manipulation of all forms of life, from simple bacteria to plants and animals. It also addresses the most important social, ethical, political, economic, and other issues raised by this form of technology. The great strides made in our understanding of the structure and function of DNA in recent decades have led to applying this invaluable knowledge to use in serving humanity. For example, recent discoveries in the field of genetic editing have created the potential for the creation of life forms de novo, a possibility that results in profound ethical issues for the human race that are jus...
