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Studies in gender in medieval culture have tended to focus on femininity, however the study of medieval masculinities has developed greatly over the last few years. Holiness and Masculinity in the Middle Ages is the first volume to concentrate on this specific aspect of medieval gender studies, and looks at the ways in which varieties of medieval masculinity intersected with concepts of holiness. Patricia Cullum and Katherine J. Lewis have collected an exceptional group of essays that explore differing notions of medieval holiness, understood variously as religious, saintly, sacred, pure, morally perfect, and consider topics such as significance of the tonsure, sanctity and martyrdom, eunuch saints, and the writings of Henry Suso. Holiness and Masculinity in the Middle Ages deals with a wide variety of texts and historical contexts, from Byzantium to Anglo-Saxon and late-medieval England.
Gene therapy is at the forefront of current techniques that aim to re-establish functional connectivity, after an insult to the brain, spinal cord or peripheral nerves. Gene therapy makes the most of the existing cellular machinery and anatomical networks to facilitate molecular changes in DNA, RNA and proteins aiming to repair these disrupted connections. For instance, gene therapy is currently being used to target genes in conditions including spinal cord injury, amyotrophic lateral sclerosis, spinal muscular atrophy, stroke and multiple sclerosis, amongst others. The various delivery routes include viral-vectors, genetically modified cellular implants, naked DNA/RNA, liposomes, Cre-Lox re...